1. Describe the different levels of organization of skeletal muscle

2. List the major properties of a skeletal muscle cell

3. Describe a sarcomere. Be able to label and identify the A band, I band, H zone, Z line, and M line.

4. Describe the thick filament. Identify the two binding sites and their functions.

5. Describe the thin filaments. Name the three proteins found together in the thin filaments and describe the

function of each.

6. Describe the sliding-filament mechanism of muscle contraction

7. Describe the steps of the cross-bridge cycle

8. Describe the role of calcium, troponin, and tropomyosin in cross-bridge cycling

9. Describe the role of ATP in contraction and relaxation

10. Describe the excitation-contraction coupling mechanism for skeletal muscle

11. Explain the time relationship between an action potential in the skeletal muscle membrane and the

contraction

12. Compare contraction to relaxation time

13. Describe the relationship between the sarcolemma, t-tubules, and sarcoplasmic reticulum, structurally and

functionally

14. Define a twitch contraction

15. Describe the role of ATP in muscle contraction/relaxation

16. Explain the 3 energy sources for muscle contraction and when each is utilized

17. Describe muscle fatigue

18. Compare fast vs. slow fibers

19. Compare oxidative vs. glycolytic fibers

20. Compare/contrast the 3 muscle fiber types

21. Describe the relationship between muscle length and strength of contraction

22. Define summation and tetanus. How are they related to strength of contraction?

23. Define a motor unit

24. Define motor recruitment. What effect does recruitment have on strength of contraction?

25. Define isometric and isotonic contractions. Understand the role of each in muscle contraction.

26. Describe the effect of the load on the velocity of contraction

27. Describe the movement of the skeleton with muscle contraction

28. Describe the structure of smooth muscle and compare it to skeletal muscle

29. Describe the excitation-contraction coupling mechanism for smooth muscle

30. Compare/contrast single unit to multi-unit smooth muscle

31. Compare/contrast pacemaker potentials to slow-wave potentials

32. Describe the extrinsic control of smooth muscle

33. Compare/contrast cardiac muscle to smooth and skeletal muscle