BMD 330: Human Physiology

Chapter 15 Objectives

Blood Flow and the Control of Blood Pressure

Introduction to Circulatory System

1. Describe the anatomy of the circulatory system. What is the path of blood flow? When is the blood

oxygenated or deoxygenated?

2. Compare/contrast the anatomy of the different types of blood vessels.

3. Define the microcirculation

Arteries

4. Describe elastic properties of arteries.

5. Define systolic and diastolic blood pressure.

6. Define mean arterial pressure. Know how to estimate mean arterial pressure and pulse pressure from

measures of systolic and diastolic blood pressures.

7. Understand the method of sphygmomanometry to measure blood pressure.

Arterioles

8. Describe resistant properties of arterioles.

9. Define vasodilation and vasoconstriction.

10. Define arteriolar tone.

11. Describe intrinsic control mechanisms of resistance and their purpose

12. List stimuli causing vasodilation

13. Describe extrinsic control mechanisms of resistance and their purpose

Capillaries

14. Compare the anatomy of continuous and fenestrated capillaries. Where is each type located?

15. Describe the anatomical features of capillaries that favor exchange between blood and tissue

16. Describe the regulation of blood flow through capillaries

17. Describe the velocity of blood flow through the blood vessels

18. Describe movement of molecules between blood and interstitial fluid: diffusion, vesicle transport,

mediated transport, and bulk flow

19. Describe intercellular clefts and how they differ in the liver and brain

20. Describe the function of bulk flow

21. Describe the movement by bulk flow based on Starling’s forces

22. Define colloid osmotic pressure, filtration and absorption.

23. Define edema. List some causes of edema.

Veins

24. Describe the compliant properties of veins and how veins function as a blood reservoir

25. Describe venous pressure and ways venous pressure can be increased to facilitate venous return.

Lymphatics

26. Describe the anatomy and function of the lymphatic system

27. Describe mechanisms to facilitate return of lymph to the circulatory system.

Blood Pressure

28. Define the driving force for blood flow through the circulatory system

29. Define the relationship between mean arterial pressure, cardiac output, and total peripheral resistance.

30. Describe short-term regulation of mean arterial pressure.

31. Identify the high pressure baroreceptors.

32. Describe the response of baroreceptors and their associated afferents to changes in mean arterial pressure.

33. Describe the effects of the autonomic nervous system on mean arterial pressure.

34. Describe long-term regulation of mean arterial pressure.

Cardiovascular Diseases

35. Describe cardiovascular diseases. What are some of the risk factors.

36. Define hypertension

37. Describe the development of atherosclerosis