BMD 330: Human Physiology
Chapter 15 Objectives
Blood Flow and the Control of Blood Pressure
Introduction to Circulatory System
1. Describe the anatomy of the circulatory system. What is the path of blood flow? When is the blood
oxygenated or deoxygenated?
2. Compare/contrast the anatomy of the different types of blood vessels.
3. Define the microcirculation
Arteries
4. Describe elastic properties of arteries.
5. Define systolic and diastolic blood pressure.
6. Define mean arterial pressure. Know how to estimate mean arterial pressure and pulse pressure from
measures of systolic and diastolic blood pressures.
7. Understand the method of sphygmomanometry to measure blood pressure.
Arterioles
8. Describe resistant properties of arterioles.
9. Define vasodilation and vasoconstriction.
10. Define arteriolar tone.
11. Describe intrinsic control mechanisms of resistance and their purpose
12. List stimuli causing vasodilation
13. Describe extrinsic control mechanisms of resistance and their purpose
Capillaries
14. Compare the anatomy of continuous and fenestrated capillaries. Where is each type located?
15. Describe the anatomical features of capillaries that favor exchange between blood and tissue
16. Describe the regulation of blood flow through capillaries
17. Describe the velocity of blood flow through the blood vessels
18. Describe movement of molecules between blood and interstitial fluid: diffusion, vesicle transport,
mediated transport, and bulk flow
19. Describe intercellular clefts and how they differ in the liver and brain
20. Describe the function of bulk flow
21. Describe the movement by bulk flow based on Starling’s forces
22. Define colloid osmotic pressure, filtration and absorption.
23. Define edema. List some causes of edema.
Veins
24. Describe the compliant properties of veins and how veins function as a blood reservoir
25. Describe venous pressure and ways venous pressure can be increased to facilitate venous return.
Lymphatics
26. Describe the anatomy and function of the lymphatic system
27. Describe mechanisms to facilitate return of lymph to the circulatory system.
Blood Pressure
28. Define the driving force for blood flow through the circulatory system
29. Define the relationship between mean arterial pressure, cardiac output, and total peripheral resistance.
30. Describe short-term regulation of mean arterial pressure.
31. Identify the high pressure baroreceptors.
32. Describe the response of baroreceptors and their associated afferents to changes in mean arterial pressure.
33. Describe the effects of the autonomic nervous system on mean arterial pressure.
34. Describe long-term regulation of mean arterial pressure.
Cardiovascular Diseases
35. Describe cardiovascular diseases. What are some of the risk factors.
36. Define hypertension
37. Describe the development of atherosclerosis