BMD 330: Human Physiology

Chapter 17 Objectives

Respiratory Physiology

Overview

1. Describe the various functions of the respiratory system

2. Compare cellular to external respiration

3. Describe the 4 processes of external respiration

Anatomy

4. Describe the anatomy of the respiratory system

5. Compare the conducting system to the alveoli

6. Compare/contrast type I and type II alveolar cells

7. Describe the pulmonary circulation

Gas Laws

8. Describe the pressures in the respiratory system and how they compare to atmospheric pressure

9. Define Dalton’s Law

10. Describe the mixture of gases in the atmosphere

11. Describe air flow due to pressure gradients

12. Describe Boyle’s Law

13. Describe the solubility of a gas in a solution

Ventilation

14. Explain the process of inspiration and expiration

15. Name the muscle of inspiration and expiration

16. Compare resting to active expiration

17. Describe the pressure changes occurring during ventilation

18. Define lung compliance

19. Explain the function of surfactant

20. Describe the resistance to air flow. Define bronchoconstriction and bronchodilation

Lung Volumes

21. Describe the use of spirometry to measure lung volumes/capacities

22. Define the different lung volumes and capacities

23. Define the anatomical dead space

24. Compare/contrast minute ventilation to alveolar ventilation

25. Define eupnea, hyperpnea, hyperventilation, hypoventilation, dyspnea, apnea

26. Describe the relationship between ventilation and perfusion

Gas Exchange

27. Describe the forces for diffusion of gases

28. Compare diffusion in lungs vs. systemic tissues

Gas Transport

29. Describe the role of hemoglobin in the transport of oxygen, carbon dioxide, and H+

30. Describe the oxygen-hemoglobin dissociation curve

31. Explain the effects of temperature, pH, and 2,3-DPG on the oxygen-hemoglobin dissociation curve

32. Describe the transport of carbon dioxide in blood

33. Explain the reaction converting carbon dioxide to bicarbonate and H+. Where is carbonic anhydrase?

Regulation of Ventilation

34. Describe the respiratory control centers in the brain stem

35. Compare/contrast central and peripheral chemoreceptors