BMD 330: Human Physiology
Chapter 17 Objectives
Respiratory Physiology
Overview
1. Describe the various functions of the respiratory system
2. Compare cellular to external respiration
3. Describe the 4 processes of external respiration
Anatomy
4. Describe the anatomy of the respiratory system
5. Compare the conducting system to the alveoli
6. Compare/contrast type I and type II alveolar cells
7. Describe the pulmonary circulation
Gas Laws
8. Describe the pressures in the respiratory system and how they compare to atmospheric pressure
9. Define Dalton’s Law
10. Describe the mixture of gases in the atmosphere
11. Describe air flow due to pressure gradients
12. Describe Boyle’s Law
13. Describe the solubility of a gas in a solution
Ventilation
14. Explain the process of inspiration and expiration
15. Name the muscle of inspiration and expiration
16. Compare resting to active expiration
17. Describe the pressure changes occurring during ventilation
18. Define lung compliance
19. Explain the function of surfactant
20. Describe the resistance to air flow. Define bronchoconstriction and bronchodilation
Lung Volumes
21. Describe the use of spirometry to measure lung volumes/capacities
22. Define the different lung volumes and capacities
23. Define the anatomical dead space
24. Compare/contrast minute ventilation to alveolar ventilation
25. Define eupnea, hyperpnea, hyperventilation, hypoventilation, dyspnea, apnea
26. Describe the relationship between ventilation and perfusion
Gas Exchange
27. Describe the forces for diffusion of gases
28. Compare diffusion in lungs vs. systemic tissues
Gas Transport
29. Describe the role of hemoglobin in the transport of oxygen, carbon dioxide, and H+
30. Describe the oxygen-hemoglobin dissociation curve
31. Explain the effects of temperature, pH, and 2,3-DPG on the oxygen-hemoglobin dissociation curve
32. Describe the transport of carbon dioxide in blood
33. Explain the reaction converting carbon dioxide to bicarbonate and H+. Where is carbonic anhydrase?
Regulation of Ventilation
34. Describe the respiratory control centers in the brain stem
35. Compare/contrast central and peripheral chemoreceptors