1. Describe the fluid-mosaic model of membrane structure

2. Describe the 3 major components of the cell membrane and list the functions of each

a. Phospholipids

b. Proteins

c. Carbohydrates

3. Describe the different body fluid compartments

4. Describe the selective permeability of the cell membrane

5. Explain how molecules, charged or uncharged, move by diffusion

6. Understand Fick’s Law of Diffusion

7. Explain the role of proteins in the movement of molecules across membranes

8. Compare/contrast facilitated diffusion, primary active transport and secondary active transport

9. Define symport and antiport

10. Describe the Na/K-ATPase

11. Describe the role of Ca-ATPases in maintaining a low [Ca] in the cytosol

12. Explain the role of sodium in secondary active transport

a. Define co-transport with sodium

b. Define counter-transport with sodium

13. Explain where the energy is needed for secondary active transport

14. Describe vesicular transport across membranes

a. Phagocytosis

b. Endocytosis

c. Exocytosis

15. Describe movement across epithelia

16. Describe the distribution of water and solutes across cell membranes

17. Explain the movement of water across membranes

18. Define osmolarity and tonicity

19. Describe the effects of tonicity on cell volume

20. Describe the properties of electricity and how they apply to the cell

21. Understand the relationship between voltage, current and resistance (Ohm’s Law)

22. Describe the membrane potential

23. Describe the role of concentration gradients and permeabilities for sodium and potassium in determining

the resting membrane potential

24. Describe the role of the Na/K-ATPase in establishing/maintaining the resting membrane potential

25. Understand the meaning of the Nernst equation and the equilibrium potential

26. Understand the forces (chemical vs. electrical) for ion movement