BMD 330: Human Physiology

Chapter 8 Objectives

The Nervous System

Organization of the Nervous System

1. Describe the organization of the nervous system

2. Label the different parts of a neuron and describe the functions of each

3. Define neuron, nerve, nerve fiber, pathway, tract, commissure, ganglia, nuclei, afferent, efferent, and

interneurons

4. Name the different classes of glial cells and describe the functions of each

Electrical Signals in the Nervous System

5. Describe ion channels and how they can open or close

6. Define excitable tissue

7. Compare hyperpolarization to depolarization.

8. Define graded potentials

9. Describe the decremental property of graded potentials

10. Compare/contrast temporal to spatial summation

11. Define action potentials

12. Describe basic properties of an action potential

13. Describe the ion permeability changes responsibility for each phase of an action potential

14. Describe the movement of ions during each phase of an action potential

15. Describe the voltage-dependent activation and inactivation of sodium gates

16. Compare/contrast the all-or-none property of action potentials to graded potentials

17. Define the threshold for initiating an action potential

18. Define the absolute and relative refractory periods and describe the causes of each

19. Describe frequency coding

20. What is the role of the Na/K-ATPase in action potentials?

21. Describe action potential propagation by local current flow

22. Describe myelin formation in the peripheral and central nervous systems

23. Describe saltatory conduction

24. Describe the mechanisms for initiating an action potential

Cell-to-Cell Communication

25. Describe the functional anatomy of chemical synapses

26. Describe the process of synaptic communication

27. Describe an excitatory post-synaptic potential

28. Describe an inhibitory post-synaptic potential

29. Define integration, convergence, and divergence

30. Compare/contrast temporal and spatial summation of synaptic potentials

31. Compare/contrast neurotransmitters and neuromodulators

32. Describe in detail the neurotransmitter acetylcholine

a. Synthesis

b. Release

c. Termination of action

33. Name and briefly describe the other classes of neurotransmitters

34. Compare/Contrast Fast vs. Slow Responses in post-synaptic cell