| INTERDISCIPLINARY
BASIC MEDICAL SCIENCE (IDL) |
| |
| IDL 570
|
Medical
Pathology |
7 cr |
|
| The
course is taught as an introduction to the scientific
study of the diseases of man by developing working
definitions and classifications of disease on
the basis of known causes and effects. After surveying
the structural changes characterizing disease,
the mechanisms involved in clinical and laboratory
manifestations are analyzed for major human diseases. |
| |
| IDL 571 |
Mouse
Models in Biomedical Research |
3 cr |
|
| This
course utilizes the primary scientific literature
to provide students with in-depth knowledge regarding
the development and utilization of mouse models
in biomedical research. Students are required
to actively participate in class discussions,
present scientific papers, and develop a research
project that utilizes mouse models. |
| |
| IDL 576 |
Literature
Reports |
1 cr |
|
| Students
in the first year interdisciplinary core curriculum
and faculty participate in reading and discussion
of current literature. The goal of this course
is to maintain the faculty's and students' level
of information at a "state-of-the-art"
in both methods and theory in interdisciplinary
biomedical research and to develop students' critical
skills in reviewing the literature. |
| |
| IDL 577 |
Introduction
to Research Methods |
2 cr |
|
| Theoretical
and practical training in basic skills utilized
in basic medical science research laboratories,
for students entering the first year interdisciplinary
curriculum. Discussion of regulatory issues in
biomedical research will be interwoven with hands-on
laboratory exercises. Offered concurrently with
IDL 580. |
| |
| IDL 580
|
Fundamentals
of Basic Medical Sciences I |
8 cr |
|
| First
of a two-semester sequence designed for students
in the first year interdisciplinary curriculum.
In depth exploration of the fundamentals of biochemistry,
cell biology and molecular biology prerequisite
to advanced study of basic medical sciences. Didactic
lectures will be complemented with discussions
of the literature. |
| |
| IDL 581
|
Fundamentals
of Basic Medical Sciences II |
8 cr |
|
| Second
of a two-semester sequence designed for students
in the first year interdisciplinary curriculum.
Detailed exploration of the fundamentals of microbiology
and immunology, developmental biology, integrative
systems physiology, and mechanisms of drug action
prerequisite to advanced study of basic medical
sciences. Didactic lectures will be complemented
with discussions of the literature. Prerequisite:
Fundamentals of Basic Medical Science I (IDL 580). |
| |
| IDL 590 |
Special
Topics |
1-3 cr |
|
| In
depth tutorial exposure to specific interdisciplinary
areas. Student and/or faculty presentations followed
by group discussions examine the subject matter
in an area of current interest. Credit and titles
are arranged with faculty. |
| |
| IDL 594
|
Directed
Studies |
1-6 cr |
|
| Students
participate in research under the direction of
a graduate faculty member. This course should
be taken by students in the first year interdisciplinary
core curriculum completing laboratory rotations
and until a mentor for advanced study is defined. |
|
| IDL
630 |
Lung
Biology |
4
cr |
|
| This
course introduces an advanced level of lung physiology.
An understanding of fundamental lung development,
anatomy, and cell and organ physiology is emphasized.
The course consists of lectures and written assignments
and essay exams. Reading assignments are from
the primary literature. Prerequisite: Completion
of Interdisciplinary Core Program, including IDL
580, 581, or permission of Course Director. |
|
| IDL
631 |
Lung
Pathobiology |
4
cr |
|
| This
course builds on an in-depth understanding of
normal lung biochemistry, cell biology, pharmacology,
and physiology to examine lung disease. Emphasis
is given on understanding mechanism(s) underlying
the genetic, cell biology, anatomy and physiology
of disease development and progression. Current
therapeutic interventions are discussed. Clinical
correlations are utilized to track signs and symptoms
of specified diseases, and provide a framework
for treatment options. The course consists of
lectures and written assignments and essay exams.
Reading assignments are exclusively from the primary
literature. Prerequisite: Lung Biology (IDL 630)
or permission of Course Director. |
|
| IDL
635 |
Advanced
Signal Transduction |
4
cr |
|
| This
course builds on signal transduction topics discussed
in the Fundamentals course (IDL 580, 581). The
mechanisms of more generalized signaling pathways
(e.g., G-protein coupled pathways) to specific
signaling pathways (e.g., TGF/BMP family) will
be discussed. Signal transduction pathways will
be examined using classic literature references,
from the molecular details of pathway components
to the effects on the organ system. The course
consists of lectures, student presentations, and
assay/problem solving examinations. Prerequisites:
IDL 580, 581, or permission of Course Director. |
| |
| IDL 780
|
Applications
in Biomedical Statistics |
3 cr |
|
| The
course treats the conception, construction, criticism,
and deployment of statistical models of biomedical
data. Models of dose-response, identification,
and survival are developed and applied to laboratory,
clinical, and epidemiological data. The course
covers linear, generalized linear, and nonlinear
models of continuous, discrete, and censored data,
and includes topics in experimental design, regression
diagnostics, salvage of weak parameter estimates,
and meta-analysis. The course is organized, for
the greater part, on a case-study format. Prerequisite:
A computer applications course. |
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