Diego Alvarez, M.D., Ph.D.

Diego Alvarez, M.D., Ph.D.
Assistant Professor
Phone (251) 460-6392
Fax (251) 460-7452
dalvarez@jaguar1.usouthal.edu

EDUCATION
1988 - 1993	MD, Universidad Libre de Colombia, Cali, Colombia

1993 - 1994	Medical intern, Instituto de los Seguros Sociales, Cali, Colombia

1995	English as a Second Language, University of South Alabama, Mobile, Alabama

1996 - 1997	Emergency room trainee, Universidad Santiago de Cali - Hospital San Juan de Dios, Cali, Colombia

1997 - 1998	Diploma in University Teaching Education, Universidad Santiago de Cali, Cali, Colombia

2000 - 2005	PhD in Basic Medical Sciences (Physiology), University of South Alabama, Mobile, Alabama

2005 - 2007	Postdoctoral fellow, Center for Lung Biology, University of South Alabama, Mobile, Alabama

PROFESSIONAL EXPERIENCE
1997 - 1999	Assistant Professor (equivalent to), Department of Basic Medical Sciences, College of Dentistry and Allied Health, Universidad Santiago de Cali, Cali, Colombia
1998 - 1999	Health Care Center Medical Coordinator, Universidad Santiago de Cali, Cali, Colombia
2007 - Current	Assistant Professor, Department of Internal Medicine and Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, Alabama

AWARDS/HONORS
1998	Distinguished Health Care Physician, Universidad Santiago de Cali
2002	Caroline Tum Suden-Frances Hellebrandt Professional Opportunity Award, American Physiological Society
2003	Phi Beta Delta Honor Society for International Scholars, University of South Alabama
2003	Predoctoral Fellowship Award (0315049B), Southeast Affiliate American Heart Association (2003 – 2005)
2004	Presidential Student Award, Microscopy Society of America
2004	Microscopy and Microanalysis 2004 Travel Award, Southeast Microscopy Society of America
2005	Research Recognition Award, Respiratory Section, American Physiological Society
2006	August Krogh Young Investigator Award, Microcirculatory Society
2006	Caroline Tum Suden-Frances Hellebrandt Professional Opportunity Award, American Physiological Society
2006	Young Investigator Award, Society for Experimental Biology and Medicine
2006	Research Recognition Award, Respiratory Section, American Physiological Society
2006	Elected Sigma Xi member
2008	Parker B. Francis Fellowship Award, Parker B. Francis Foundation
2009	Star Reviewer, American Journal of Physiology Lung Cell and Molecular Physiology

TEACHING ACTIVITIES

Previous:

1997 - 1998	Course director, General Physiology: Course offered to undergraduate Allied Health and Dentistry majors, Universidad Santiago de Cali, Cali, Colombia
1998 - 1999	Course director, Respiratory Physiology: Course offered to undergraduate Allied Health majors, Universidad Santiago de Cali, Cali, Colombia
2002	Instructor, Physiology laboratory course: Course offered to undergraduate Basic Medical Science majors, University of South Alabama, Mobile, Alabama
2002 - 2005	Teaching Assistant, Electrocardiogram laboratory, Medical Physiology Course PHY 121: Course offered to Medical students, University of South Alabama, Mobile, Alabama
2003 - 2005	Lecturer, Renal Physiology. Biomedical Enrichment and Recruitment (BEAR) program: Course offered to minority students, University of South Alabama, Mobile, Alabama
2008	Course director, IDL 650-Spring 2008: Special Topic on Stem Cells. Course offered to Basic Medical Sciences graduate students, University of South Alabama, Mobile, Alabama

Current:

2005 -	Teaching Assistant, Lung volumes laboratory, Medical Physiology Course PHY 121: Course offered to Medical students, University of South Alabama, Mobile, Alabama
2006 -	Lecturer, Lung Pathobiology IDL 631: Course offered to Basic Medical Sciences graduate students, University of South Alabama, Mobile, Alabama
2007 -	Lecturer, Problem-based small group discussions. Pharmacology PHM 221: Course offered to Medical students, University of South Alabama, Mobile, Alabama
2007 -	Lecturer, Lung Biology IDL 630: Course offered to Basic Medical Sciences graduate students, University of South Alabama, Mobile, Alabama
2009 -	Lecturer, Fundamentals of Biomedical Science II IDL 581. Course offered to Basic Medical Sciences graduate students, University of South Alabama, Mobile, Alabama
2009 -	Lecturer, Summer Research Seminar Program. Research program offered to Medical and undergraduate students

GRANT ACTIVITIES

Current/Active:

AHA 0835134N Alvarez (PI) 07/01/2008 – 06/30/2012
AHA Scientist Development Grant
“Infusion of resident endothelial progenitors promotes repair of microvascular barrier during acute lung injury”.
The goal of this project is to determine whether use of resident microvascular endothelial progenitor cells as a cell-based therapy constitutes a therapeutic alternative for the treatment of lung injury.
Role: Principal Investigator

RO1 HL094455 Rich (PI) 09/01/2009 – 08/31/2011
NIH/HLBI
“cAMP phosphodiesterase and lung endothelial cell permeability”.
The goal of this project is to study the role of the cAMP phosphodiesterase PDE7 in regulating barrier function in pulmonary artey endothelial cells.
Role: Co-Investigator

Submitted/Pending:

RO1 HL Fouty (PI)
Pending
NIH/HLBI
“HIF-1 alpha and pulmonary vascular repair”.
The goal of this project is to study the contribution of hypoxia inducible factor one alpha in dictating the recovery of pulmonary endothelial cells during acute lung injury.
Role: Co-Investigator

RO1 HL Creighton (PI)
Pending
NIH/HLBI
“AMPK A1 and N-cadherin form a functional complex essential for lung endothelial barrier permeability”.
The goal of this project is to study the contribution of AMPK1 in dictating barrier integrity of pulmonary endothelial cells following lung injury.
Role: Co-Investigator

Past/Others:

1.	PBF fellowship Alvarez (PI) 06/01/2008 – 05/31/2011 Parker B. Francis Fellowship “Infusion of resident microvascular endothelial progenitor cells promotes repair of the pulmonary microvascular barrier following Pseudomonas aeruginosa-induced lung injury”. The goal of this project was to determine whether use of resident microvascular endothelial progenitor cells as a cell-based therapy constitutes a therapeutic alternative for the treatment of lung injury. Role: Principal Investigator Status: Relinquished due to scientific overlap with AHA Scientist Development Grant

2.	AHA-SE 0315049B Alvarez (PI) 07/01/2003 – 06/30/2005 AHA Predoctoral Fellowship Award “Role of P450 arachidonic acid metabolites in regulation of pulmonary endothelial cell permeability”. The goal of this project was to determine whether P450 arachidonic acid metabolites contributed to pulmonary endothelial barrier disruption resulting in increased fluid filtration and pulmonary edema. Role: Principal Investigator Status: Completed

3.	P40 RR020052 Abee (PI) 07/23/2004 – 05/31/2009 NIH/NCRR “Owl Monkey Breeding and Research Resource”. The goal of this project is to create a self-sustaining breeding resource of Owl monkeys that meet the needs for the use of this species in Basic Research. Role: Consultant (no cost) Status: Completed

PUBLICATIONS

ARTICLES

1.	Alvarez, D.F., E-A.B. Gjerde, and M.I. Townsley. Role of EETs in regulation of endothelial permeability in rat lung. Am. J. Physiol. Lung Cell Mol. Physiol. 286 (2): L445-L451, 2004.
2.	Alvarez, D.F., J.A. King, and M.I. Townsley. Evaluation of endothelial permeability by a corrosion casting technique. Microsc. Microanal. 10 (Suppl. 2): 200-201, 2004.
3.	Wu, S., E.A. Cioffi, D. Alvarez, S.L. Sayner, H. Chen, D.L. Cioffi, J.A. King, J.R. Creighton, M.I. Townsley, S.R. Goodman, and T. Stevens. Essential role of a Ca2+ selective, store operated current (ISOC) in endothelial cell permeability. Determinants of the vascular leak site. Circ. Res. 96 (8): 856-863, 2005.
4.	Alvarez, D.F., J.A. King, and M.I. Townsley. Resistance to store depletion-induced endothelial injury in rat lung after chronic heart failure. Am. J. Respir. Crit. Care Med. 172: 1153-1160, 2005.
5.	Alvarez, D.F., J.A. King, D. Weber, E. Addison, W. Liedtke, and M.I. Townsley. Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury. Circ. Res. 99 (9): 988-995, 2006. An editorial accompanied the article: Curry, F-R.E. and C.A. Glass. TRP channels and the regulation of vascular permeability: New insights from the lung microvasculature. Circ. Res. 99 (9): 915-917, 2006.
6.	Townsley, M.I., J.A. King, and D.F. Alvarez. Ca2+ channels and pulmonary endothelial permeability: insights from study of intact lung and chronic pulmonary hypertension (Review). Microcirculation. 13 (8): 725-39, 2006.
7.	Lowe, K., D.F. Alvarez, J. A. King, and T. Stevens. Phenotypic heterogeneity in lung capillary and extra-alveolar endothelial cells. Increased extra-alveolar endothelial permeability is sufficient to decrease compliance. J. Surg. Res. 143(1): 70-77, 2007.
8.	Hamanaka K., M-J. Jian, D.S. Weber, D.F. Alvarez, M.I. Townsley, A.B. Al-Mehdi, J.A. King, W. Liedtke, and J.C. Parker. TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. Am. J. Physiol. Lung Cell Mol. Physiol. 293 (4): L923-L932, 2007.
9.	Klinger J.R., J.D. Murray, B. Casserly, D.F. Alvarez, J. King, S.S. An, G. Choudhary, A. N. Owusu-Sarfo, R. Warburton, and E.O. Harrington. Rottlerin causes pulmonary edema in vivo: a possible role for PKCδ. J. Appl. Physiol. 103 (6): 2084-2094, 2007.
10.	Alvarez, D.F., L. Huang, J.A. King, M.C. Yoder, and T. Stevens. Lung microvascular endothelium is enriched with progenitor cells that exhibit rapid vasculogenic capacity. Am. J. Physiol. Lung Cell Mol. Physiol. 294 (3): L419-L430, 2008. An editorial accompanied the article: Bhattacharya, J. Lung neovascularization: A tale of two circulations. Am. J. Physiol. Lung Cell Mol. Physiol. 294 (3): L419-L430, 2008.
11.	Clark, J., D.F. Alvarez, M. Alexeyev, J.A. King, L. Huang, M.C. Yoder, and T. Stevens. Regulatory role for nucleosome assembly protein-1 in the proliferative and vasculogenic phenotype of pulmonary endothelium. Am. J. Physiol. Lung Cell Mol. Physiol. 294 (3): L431-L439, 2008.

12.	Troyanovsky, B., D.F. Alvarez, J.A. King, and K. Schaphorst. Thrombin enhances the barrier function of rat microvascular endothelium in a PAR-1-dependent manner. Am. J. Physiol. Lung Cell Mol. Physiol. 294 (2): L266-L275, 2008.
13.	King, J., S. Agarwal, E. Syklawer, N. Prasain, H. Chen, J. Resmondo, F. McDonald, N. Bauer, D.F. Alvarez, S. Wu, T. Stevens, L. Shevde, T. Moore, and M. Townsley. Quantum Dots - Utilization in TEM. Microsc. Microanal. 14 (Suppl. 2): 702-703, 2008.
14.	Stevens, T., S. Phan, M. Frid, D. Alvarez, E. Herzog, and K. Stenmark. NIH Workshop on Lung Vascular Cell Heterogeneity: Endothelium, Smooth Muscle, and Fibroblasts (Perspective). Proc. Am. Thorac. Soc. 5 (7): 783-791, 2008.
15.	Cioffi, D., K. Lowe, D.F. Alvarez, C. Barry, and T. Stevens. TRPing on the lung endothelium. Calcium channels that regulate barrier function (Review). Antioxid. Redox Signal. (In press), 2008.
16.	Zhu, B., L. Zhang, M. Alexeyev, D.F. Alvarez, S.J. Strada, and T. Stevens. Type 5 phosphodiesterase expression is a critical determinant of the endothelial cell angiogenic phenotype. Am. J. Physiol. Lung Cell Mol. Physiol. 296(2): 220-228, 2009.
17.	Majka S. and D.F. Alvarez. Neovascular capacity of endothelial progenitor cells in the adult pulmonary circulation (Editorial). Am. J. Physiol. Lung Cell Mol. Physiol. 296 (6): 868-869, 2009.
18.	Alvarez, D.F., K. Helm, J. DeGregori, M. Roederer, and S. Majka. Publishing flow cytometry data (Review). Am. J. Physiol. Lung Cell Mol. Physiol. (In review), 2009.
19.	King, J.A., F. Tan, Z. Chambers, S. Cantrell, H. Chen, D. Alvarez, L.A. Shevde, and S.F. Ofori-Acquah. Epigenetic regulation of ALCAM/CD166 and its role in tumor cell adhesion in the pulmonary vasculature. (Submitted), 2009.
20.	Lowe, K., D.F. Alvarez, J. A. King, and T. Stevens. Perivascular cuffs impair lung compliance. (Submitted), 2009.
21.	Solodushko, V., D.F. Alvarez, R. Viator, T. Messerall, and B. Fouty. Increased Bmi-1 Levels Identify Pulmonary Artery Smooth Muscle Progenitor Cells. (Submitted), 2009.
22.	Hill K.L., P. Obrtlikova, D.F. Alvarez, J.A. King, Q. Li, J. Zhang, and D.S. Kaufman. In vitro and in vivo characterization of human embryonic stem cell-derived vascular progenitor cells (Submitted), 2009.
23.	Parra-Bonilla G., D.F. Alvarez, and T. Stevens. Warburg effect in pulmonary microvascular endothelial cells (Submitted), 2009.
24.	Alvarez, D.F., K. Lowe, J.A. King, M.C. Yoder, J.P. Weiner-Kronish, and T. Stevens. Resident microvascular endothelial progenitor cells restore the disrupted barrier after Pseudomonas aeruginosa-induced acute lung injury (In preparation).
25.	Alvarez, D.F. Cell-based therapies in the horizon for treating ALI/ARDS. (In preparation), 2009.

ABSTRACTS

A1.	Alvarez, D., and M.I. Townsley. Are P450 epoxygenase arachidonic acid derivatives (EETs) involved in lung endothelial permeability after chronic heart failure? Proceedings of the Gulf Coast Physiological Society meeting, 2002.
A2.	Alvarez, D., and M.I. Townsley. Are P450 epoxygenase arachidonic acid derivatives (EETs) involved in lung endothelial permeability after chronic heart failure (HF)? FASEB J. 164: A402, 2002.
A3.	Alvarez, D., and M.I. Townsley. Role of P450 epoxygenases in regulation of lung endothelial permeability. Proceedings of the Grover conference on pro-inflammatory signaling mechanisms in the pulmonary circulation, 2002.
A4.	Alvarez, D., and M.I. Townsley. Role of P450 arachidonic acid metabolites in regulation of endothelial cell permeability in rat lung. FASEB J. 17: A85, 2003.

A5.	Gjerde, E.A.B., D. Alvarez, T. Stevens, and M.I. Townsley. Role of 14,15- and 11,12-epoxyeicosatrienoic acids in activation of store-operated calcium channels in rat pulmonary microvascular endothelial cells. Proceedings of the Scandinavian Congress of Physiology and Pharmacology, 2003.
A6.	Alvarez, D., J.A. King, and M.I. Townsley. Evaluation of Ca++ entry-induced lung injury in heart failure. Proceedings of the Gulf Coast Physiological Society meeting, 2004.
A7.	Alvarez, D., J.A. King, and M.I. Townsley. Structural analysis of Ca++ entry-induced pulmonary endothelial cell injury. FASEB J. (Late Breaking Abstract), 2004.
A8.	Alvarez, D., J.A. King, and M.I. Townsley. Adaptive mechanisms underlying resistance to acute lung injury in heart failure. Am. J. Resp. Crit. Care Med. 169(7): A157, 2004.
A9.	Alvarez, D., J.A. King, and M.I. Townsley. Underlying protection to store depletion-induced endothelial cell injury in rat lung after heart failure. Proceedings of the Grover Conference on genetic and environmental determinants of pulmonary endothelial cell function, 2004.
A10.	Alvarez, D., and M.I. Townsley. A novel role for TRPV4 in regulation of pulmonary endothelial permeability. Proceedings of the Gulf Coast Physiological Society meeting, 2005.
A11.	Alvarez, D., and M.I. Townsley. A novel role for TRPV4 in regulation of pulmonary endothelial permeability. FASEB J. 19: A172, 2005.
A12.	Alvarez, D., H. Chen, J.A. King, T. Stevens and M.I. Townsley. Application of vascular corrosion casting to characterize spatial injury “fingerprints” induced by Ca++ entry in rat lung endothelium. Proceedings of the Southeastern Microscopy Society 25: 2005.
A13.	Parker, J.C., D. Drake, J.A. King, D. Alvarez, M.I. Townsley, S. Yoshikawa. Vascular segmental leak in lungs after high airway pressure inflation. Microsc. Microanal. 11 (Suppl. 2) LBP 8, 2005.
A14.	Alvarez, D., J.A. King, W. Liedtke, and M.I. Townsley. Ca2+ entry via TRPV4 increases endothelial permeability in mouse lung septal capillaries. FASEB J. 20: A747, 2006.
A15	Schaphorst, K.L., D. Alvarez, B. and Troyanovsky. Thrombin enhances the barrier function of rat microvascular endothelium in a PAR1-dependent manner. Proc. Am. Thorac. Soc. 3: A307, 2006.
A16.	Lowe, K., D. Alvarez, J.C. Parker, T. Stevens. Phenotypic differences in the pulmonary vascular endothelium are revealed by leak sites and the shape of the pressure/volume curve. Proc. Am. Thorac. Soc. 3: A310, 2006.
A17.	King J.A., D. Alvarez, and M.I. Townsley. Correlative microscopic analysis of pulmonary endothelial leak sites. S.E. Biology 53 (2): 230, 2006.
A18.	Alvarez, D., M.C. Yoder, L. Huang, J.A. King, and T. Stevens. Adult microvascular endothelium is enriched with high proliferative potential progenitor cells that possess angiogenic capacity. Proceedings of the 4th annual meeting, International Society for Stem Cell Research. 101: 203, 2006.
A19.	Alvarez, D., M.C. Yoder, L. Huang, J.A. King, and T. Stevens. Adult microvascular endothelium is enriched with high proliferative potential progenitor cells that possess angiogenic capacity. Gordon Conference in Endothelial Cell Phenotypes in Health and Disease. Biddeford, Maine, 2006.
A20.	Alvarez D., M. Yoder, L. Huang, and T. Stevens. Presence of high proliferative potential resident endothelial progenitor cells within the lung microcirculation. FASEB J. 21 (6): A1434-a, 2007.
A21.	Alvarez D., M. Yoder, L. Huang, J.A. King, and T. Stevens. Lung microvascular resident endothelial progenitor cells exhibit high vasculogenic capacity. FASEB J. 21 (6): A856-a, 2007.
A22.	Clark, J., D. Alvarez, J. A. King, M. Alexeyev, M. Yoder, L. Huang, and T. Stevens. Essential role of nucleosome assembly protein in pulmonary endothelial vasculogenesis. FASEB J. 21 (6): A1434, 2007.

A23.	Hamanaka K., D. Alvarez, M.I. Townsley, W. Liedtke, and J.C. Parker. TRPV4 regulates the calcium-dependent acute permeability increase during ventilator-induced lung injury in isolated mouse lungs. Proc. Am. Thorac. Soc. 175: A222, 2007.
A24.	Casserly B., J.D. Murray, D. Alvarez, J.R. Klinger, and E.O. Harrington. Rottlerin causes pulmonary edema in vivo: a possible role for PKCδ. Proc. Am. Thorac. Soc. 175: A235, 2007.
A25.	D. Alvarez, M.K. ElZarrad, J.A. King, J. Wiener-Kronish, M.C. Yoder, and T. Stevens. Infusion of Resident Microvascular Endothelial Progenitor Cells promotes repair of the endothelial barrier during acute lung injury. Proc. Am. Thorac. Soc. 117: A230, 2008.
A26.	D. Alvarez, D. Robinson, M.K. ElZarrad, T. Stevens, and J.A. King. Apical secretion of collagen II from endothelial cells precedes blood vessel formation during postnatal vasculogenesis. FASEB J. 22: 1178.13, 2008.
A27.	D. Alvarez, M.C. Yoder, M. Alexeyev, and T. Stevens. Nucleosome assemble protein 1 (NAP-1) determines the progenitor status of endothelial cells. FASEB J. 22: 1178.12, 2008.
A28.	G. Parra-Bonilla, D. Alvarez, D. Cioffi, and T. Stevens. Lung microvascular endothelial cells utilize aerobic glycolysis (e.g. Warburg effect) to sustain rapid proliferation. FASEB J. 22: 1178.9, 2008.
A29.	G. Parra-Bonilla, D. Alvarez, D. Cioffi, and T. Stevens. Glucose restriction inhibits glycolytix flux and limits proliferation in lung microvascular endothelial cells. FASEB J. 22: 1178.10, 2008.
A30.	N. Prasain, D. Alvarez, D.W. Frank, and T. Stevens. Exo Y increases Pseudomonas aeruginosa virulence. FASEB J. 22: 928.6, 2008.
A31.	King J., S. Agarwal, E. Syklawer, N. Prasain, H. Chen, J. Resmondo, F. McDonald, N. Bauer, D. Alvarez, S. Wu, T. Stevens, L. Shevde, T. Moore, and M. Townsley. Quantum Dots–TEM Applications. Proceedings of the Southeastern Microscopy Society 28: 2008.
A32.	D. Alvarez, M.C. Yoder, M. Alexeyev, and T. Stevens. Nucleosome assemble protein 1 (NAP-1) determines the progenitor status of endothelial cells. Gordon Conference in Endothelial Cell Phenotypes in Health and Disease. Biddeford, Maine, 2008.
A33.	Hill K.L., P. Obrtlikova, D. Alvarez, J.A. King, Q. Li, J. Zhang, and D.S. Kaufman. In vitro and in vivo characterization of human embryonic stem cell-derived CD34+ cells that function as pericytes with endothelial cell and smooth muscle cell potential. Blood 112(11): 693, 2008.
A34.	Alvarez, D., G. Parra, M. Alexeyev, and J.A.King. NAP1-L1 determines the progenitor status of pulmonary endothelium. FASEB J. 23: 771.2, 2009.
A35.	Parra-Bonilla G, D. Alvarez, A-B. Al-Medhi, and T. Stevens. Essential role of lactate in controlling the rapid proliferation of pulmonary microvascular endothelial cells. FASEB J. 23: 1024.12, 2009.
A36.	J.W. Olson, A. Koloteva, G. Parra, and D. Alvarez. Ornithine Decarboxylase (ODC) regulates the proliferative phenotype of rat microvascular endothelial progenitor cells. FASEB J. 23: 771.6, 2009.

BOOKS:

Chapters:

Yoder, M.C. and D.F. Alvarez, Circulating and Vascular Progenitor Cells in Lung Injury and Pulmonary Hypertension, in: Handbook in Pulmonary Circulation and Non-Respiratory Functions. American Physiological Society, 2009 (In preparation).

Editor:

Alvarez D.F. and B.W. Fouty. Handbook in Respiratory Physiology. World Scientific, 2010 (In preparation).

INVITED LECTURES/CHAIRED SESSIONS (Extramural)

2002	Gulf Coast Physiological Society Meeting (Jackson, Mississippi): “Are P450 epoxygenase arachidonic acid derivatives (EETs) involved in lung endothelial permeability after chronic heart failure?”
2002	Experimental Biology International Meeting (New Orleans, Louisiana): “Are P450 epoxygenase arachidonic acid derivatives (EETs) involved in lung endothelial permeability after chronic heart failure (HF)?”
2003	Experimental Biology International Meeting (San Diego, California): “Role of P450 arachidonic acid metabolites in regulation of endothelial cell permeability in rat lung”
2004	Gulf Coast Physiological Society Meeting (Mobile, Alabama): “Evaluation of Ca++ entry-induced lung injury in heart failure”
2004	Microscopy and Microanalysis International Meeting (Savannah, Georgia): “Evaluation of endothelial permeability by a corrosion casting technique”
2005	Gulf Coast Physiological Society Meeting (New Orleans, Louisiana): “A novel role for TRPV4 in regulation of pulmonary endothelial permeability”
2005	Southeastern Microscopy Society Meeting (Pensacola, Florida): “Application of vascular corrosion casting to characterize spatial injury fingerprints induced by Ca++ entry in rat lung endothelium”
2005	Respiratory and Critical Care Medicine Seminar, LSU, Health Medical Center (New Orleans, Louisiana): “Regulation of pulmonary endothelial permeability by distinct Ca++ entry pathways”
2006	Experimental Biology International Meeting (San Francisco, California): “Activation of TRPV4 increases endothelial permeability in lung septal capillaries”
2006	Vascular Biology Seminar, St. Michael’s Hospital (Toronto, Canada): “Contribution of Pulmonary Microvascular Endothelium in Maintenance of Barrier Integrity and Their Reparative Capacity Following Lung Injury”
2006	Gordon conference in endothelial cell phenotypes in Health and Disease (Biddeford, Maine): “ Adult Lung microvascular endothelium is enriched with high proliferative potential progenitor cells that possess angiogenic capacity”
2007	Experimental Biology International Meeting (Washington, D.C.): “Lung microvascular resident endothelial progenitor cells exhibit high vasculogenic capacity”
2007	American Thoracic Society International Conference (San Francisco, California): “Cell-based therapies in ALI using endothelial progenitors derived from vascular wall”
2008	American Federation for Medical Research Symposium (San Diego, California): “Cell-based therapies in the horizon for treating ALI/ARDS”
2008	American Thoracic Society International Conference (Toronto, Canada): “Infusion of Resident Microvascular Endothelial Progenitor Cells promotes repair of the endothelial barrier during acute lung injury”
2008	Pulmonary Endothelial Cell Symposium (Richmond, Virginia): “Pulmonary Endothelial Stem Cells”
2008	Gordon conference in endothelial cell phenotypes in Health and Disease (Biddeford, Maine): “Nucleosome Assemble Protein 1 (NAP-1) determines the progenitor status of endothelial cells”
2008	Pulmonary conference, University of Chicago, (Chicago, Illinois): “On the hunt for restoring the Pulmonary Vascular Barrier during ALI”
2009	Experimental Biology International Meeting (New Orleans, Louisiana): “NAP1-L1 determines the progenitor status of pulmonary endothelium”
2009	American Thoracic Society Workshop on Angiogenesis in the post-natal pulmonary circulation (San Diego, California): “Angiogenic capacity of the pulmonary circulation”
2009	Poster Discussion Session - Chair: The pulmonary vasculature in acute lung injury

INVITED LECTURES (Intramural)

2003

Odyssey Program: “Systemic arterial hypertension: The hidden enemy”

2004

Odyssey Program: “Heart failure: A big heart is not necessary a good one”

2004

Pulmonary and Critical Care Medicine Division Conference: “Unveiling adaptive mechanisms to acute lung injury in heart failure”

2006

Critical Care Conference: “Exploring the role of cell based therapy in the treatment of Acute Lung Injury”

2007

Special Topics for Graduate Basic Medical Sciences trainees: “The history of ARDS”

2009

Surgery Grand Rounds: “On the hunt for restoring the Pulmonary Vascular Barrier during ALI”

MANUSCRIPT REVIEW

2006 - Current	American Journal of Physiology-Lung Cellular and Molecular Physiology
2006 - Current	Microvascular Research
2008 - Current	Translational Research
2008 - Current	American Journal of Respiratory Cell and Molecular Biology
2009 - Current	American Journal of Respiratory and Critical Care Medicine

EDITORIAL BOARDS

2009 - Current

American Journal of Physiology-Lung Cellular and Molecular Physiology

PROFESSIONAL SOCIETIES

2000 - Current	American Physiological Society
2000 - Current	Society for Experimental Biology and Medicine
2000 - Current	Federation of American Societies for Experimental Biology
2005 - Current	International Society for Stem Cell Research

INVOLVEMENT IN TRAINING

UNDERGRADUATES

Emile Addison, University of South Alabama, 2005 - 2006

Susan Weinholz, exchange student, Hochschule Magdegurg-Stendal, Germany, 2006 - 2007

Elexissca N. Morriessette, Biology major, University of South Alabama, 2008 - Current

MEDICAL STUDENTS (summer research program)

William Porr, University of South Alabama, 2003

Christopher Robin Bailey, University of South Alabama, 2006

Daniel Robinson, University of South Alabama, 2007

Sailaja Allamneni, University of South Alabama, 2008 - 2009

RESIDENT FELLOWS

Anthony J. Wright, Surgeon resident, University of South Alabama, 2007 - 2008

Tung Trang, Pulmonary and Critical Care fellow, University of South Alabama, 2008 - Current

GRADUATES:

Courtney Rothrock, Master of Science in Environmental Toxicology, University of South Alabama, 2008 - Current

NATIONAL RELEVANT LEADERSHIP SERVICES

2006 - 2009	Trainee Representative, Steering Committee, Respiratory Section-American Physiological Society
2009 - Current	Web Site Coordinator, Pulmonary Circulation Assembly-American Thoracic Society
2009 - Current	Program Committee member, Pulmonary Circulation Assembly-American Thoracic Society
2009 – Current	Planning Committee member, Pulmonary Circulation Assembly-American Thoracic Society
2009 - Current	Program Committee member, Respiratory Section-American Physiological Society
2009 - Current	Nominating Committee member, Respiratory Section-American Physiological Society

INSTITUTIONAL RELEVANT LEADERSHIP SERVICES

1997 - 1999	Academic Committee (member), Allied Health Programs (equivalent to), Universidad Santiago de Cali, Cali, Colombia
1997 - 1998	Occupational Health Committee (chair), Universidad Santiago de Cali, Cali, Colombia
2001 - 2004	Biomedical Library Committee (member), University of South Alabama, Mobile, Alabama
2002 - 2005	Biomedical Science Student Organization (Department of Physiology representing member), University of South Alabama, Mobile, Alabama
2003 - 2004	Executive Committee (member), Interdisciplinary Graduate Program in Basic Medical Sciences, University of South Alabama, Mobile, Alabama
2007 - Current	Acute Lung Injury Journal Club (director), University of South Alabama, Mobile, Alabama
2008 - 2009	Biomedical Science Student Organization (advisor), University of South Alabama, Mobile, Alabama
2009 - Current	Pulmonary & Critical Care Seminar (director), University of South Alabama, Mobile, Alabama
2009 - Current	Institutional Animal Care and Use Committee (member), University of South Alabama, Mobile, Alabama

COMMUNITY SERVICES

1997 - 1998	Health care brigade coordinator, health care unit that assisted underprivileged regions in rural areas, Cali, Colombia
1997 - 1999	Asthma Club Director, a program directed to educate families of patients with asthma. Universidad Santiago de Cali in association with Glaxo and Böehringer laboratories, Cali, Colombia
2005 - 2006	Monitor of a workshop in cardio-electrophysiology for middle school girls, Expanding Your Horizons, a community program on careers in Science, Mobile, Alabama
2004 - Current	Sponsor of underprivileged children for elementary education, Fundacion Caritas al Sol, Cali, Colombia

Last modified: Sep. 16, 2009