EDUCATION

SOCIETY MEMBERSHIPS (Past and Present)

• Eastern Society for Pediatric Research

• American Academy of Pediatrics: Committee on the Fetus and Newborn, Maryland Chapter

• Southern Society for Pediatric Research

• Alabama Society of Neonatology

• Alabama Committee on the Fetus and Newborn (2/95 – Present)

• American Thoracic Society (1996 – Present)

• Medical Association of the State of Alabama (1996 –1998)

• Mobile Pediatric Society (1995 – Present)

• Southeastern Association of Neonatologists, Inc.

• Alpha Omega Alpha Medical Honor Society (3/2002 – Present)

POSITIONS HELD

POSTGRADUATE AWARDS

CERTIFICATIONS AND LICENSURES

UNIVERSITY APPOINTMENTS

COURSES TAUGHT AT THE UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE

COMMITTEE ASIGNMENTS (University of South Alabama) ACADEMIC

HOSPITAL

DEPARTMENTAL

 
PEER REVIEW

• Journal of Perinatology
      *Acute Hemorrhagic Gastritis and Total Gastrectomy in a Preterm
         Neonate After Indomethacin Tocolytic Therapy. (10/99)
       *Caudal Regression Syndrome in Twin Pregnancy with Type II Diabetes (5/01)
       *Caudal Regression Syndrome vs. Sirenomelia: A Case Report (5/01)

• Southern Medical Journal
        *Helium Administration During High Frequency Jet Ventilation
        *Thermoregulation in the Newborn

RESEARCH INTERESTS

External High Frequency Ventilation (HFV): comparative efficacy of the various forms of external (around the chest wall) HFV. Definition of its role in management of lung surfactant depleted conditions.

Role of High Frequency Ventilation in an animal model of meconium aspiration pneumonia and pulmonary hypertension.

Role of various forms of non-conventional methods of respiratory support (i.e. high frequency ventilation, continuous flow apneic ventilation, liquid ventilation) to enhance the beneficial effect of exogenous surfactant treatment.

Role of High Frequency Ventilation in an animal model of meconium aspiration pneumonia and pulmonary hypertension.

Role of modificators of hypoxic vasoconstriction reflex on the effect of nitric oxide.

Role of macrophages in ventilator induced lung injury.

GI ischemia reperfusion injury.
  

PUBLICATIONS

1. Eyal FG, Schenker S, Polishuk W: Ectopic pregnancy-survey of 433 cases. Harefuah 10:4, 409-412, 1972 (in Hebrew)

2. Schenker S, Eyal FG, Polishuk W: Fertility after tubal pregnancy. Surgery, Gynecology and Obstetrics 135, 74-76, 1972.

3. Kapitulnik H, Simha A, Eyal FG: Gentamicin and bilirubin binding by plasma. Lancet, 12/1/95. 1972.

4. Ramo A, Slonim A, London M, Eyal FG: Hyperglycemia in acute Malathion poisoning. Israel Journal of Medical Sciences 9: 631-634, 1973.

5. Yatziv A, Eldor A, Eyal FG, Russel A: Coagulopathy in non-cirrhotic portal fibrosis. Acta Pediatrica Scandinavica 63: 151-154, 1973.

6. Shapira E, Ben Yoseph Y, Eyal FG, Russel A: Enzymatically inactive red cell carbonic anhydrase B in a family with renal tubular acidosis. Journal of Clinical Investigation 53: 59-63, 1974.

7. Sotela Avila C, Perry CM, Parvey LS, Eyal FG: Coexistent congenital cytomegalovirus and toxoplasmosis in a newborn infant. Journal of the Tennessee Medical Association 67: 588-592, 1974.

8. Korones SB, Eyal FG: Successful treatment of persistent fetal circulation with Tolazoline. Pediatric Research 9: 367, 1975.

9. Siegle R, Eyal FG, Rabinowitz JG: Air embolus following pulmonary interstitial emphysema in hyaline membrane disease. Clinical Radiology 27: 77-80, 1976.

10. Siegle R, Rabinowitz JG, Korones SB, Eyal FG: Early diagnosis of necrotizing enterocolitis. American Journal of Roentgenology 127: 629-632, 1976.

11. Ofeq I, Beachey EH, Eyal FG, Morrison JC: The postnatal development of binding of streptococci and lipoteichoic acid by oral mucosal cells of man. Journal of Infectious Diseases 135: 267-272, 1977.

12. Eyal FG, Maayan C, Godfrey S: Heart failure apparently due to overfeeding in a neonate. Archives of Disease in Childhood 5: 908-911, 1978.

13. Perlman M. Eyal FG: Retrolental Fibroplasia pediatric perspectives. Metabolic Ophthalmology 2: 321-323, 1978.

14. Eyal FG, Robinson M: High Frequency mechanical ventilation in infants with severe respiratory failure. The at risk infant. Editor: S. Harel. Excerpta Medica Amsterdam. pp. 129-132, 1979.

15. Arad I, Sagi E, Eyal FG: Plasma ascorbic acid in premature infants. International Journal Vitamin Nutrition Research 52: 50-54, 1984.

16. Eyal FG, Avital A: Apparent lack of protection to necrotizing enterocolitis by human milk. Human Milk Editor: S. Freier. Excerpta Medica Amsterdam, pp. 227-230, 1980.

17. Sadovsky E, Eyal FG, Perlman M, Beyth Y: Decreased fetal activity and fetal heart rate changes after amniocentesis complicated by fetal hemorrhage. International Journal of Gynecology and Obstetrics 19(5): 395-97, 1981.

18. Gale R, Eyal FG: The impact of integration and upgrading neonatal services on neonatal mortality. Harefuah 100: 389-391, 1981. (In Hebrew)

19. Arad I, Eyal FG: Pulmonary circulation in the neonate. Harefuah 100: 436-437, 1981. (In Hebrew)

20. Springer C, Eyal FG, Michel J: Trimethoprim-sulfamethoxazole in newborn infants. Harefuah 101: 81-84, 1981. (In Hebrew)

21. Blank A, Eyal FG, Rotenberg M, Gonen B, Chako J: Motor nerve conduction velocity in premature and newborn babies. Phronesis 2: 15-19, 1981.

22. Arad I, Eyal FG, Fainmesser PL: Umbilical care and cord separation. Archives of Diseases in Childhood 56: 887-888, 1981.

23. Sagi E, Eyal FG, Armon Y, Arad I, Robinson M: Exchange transfusion in newborn via a peripheral artery and vein. European Journal of Pediatrics 137: 283-84, 1981.

24. Eyal FG, Sagi I, Arad I, Avital A: Necrotizing enterocolitis in the very low birth weight infant: expressed breast milk feeding compared with parenteral feeding. Archives of Diseases in Childhood 57: 274-76, 1982.

25. Azoury R, Eyal FG, Springer C: 5-reductase activity in human fetal testis. International Journal of Biochemistry 14: 577-580, 1982.

26. Springer C, Eyal FG, Michel J: Pharmacology of trimethoprim-sulfamethoxazole in newborn infants. Journal of Pediatrics 100: 647-650, 1982.

27. Springer C, Eyal FG: Successful treatment of interstitial emphysema by selective intubation. Harefuah 102: 421-422, 1982. (In Hebrew)

28. Frankel D, Shapira R, Arbel T, Shapira Y, Eyal FG: The visual attention at four months of full term small for gestation age and full term appropriate for gestation age infants. Infant Behavior and Development, Editors: LP Lipsitt, TM Fields, Ablex Publishing Corp. pp. 121-129, 1982.

29. Eyal FG, Sagi I: The very low birth weight infant: 1. Guidelines for management. Harefuah 102: 530-532, 1982. (In Hebrew)

30. Sagi, Eyal FG: The very low birth weight infant: II. Long-term outcome. Harefuah 103: 22-24, 1982. (In Hebrew).

31. Tal A, Bar-Yishai, Eyal FG, Godfrey S: Lack of response to bronchodilator of airway obstruction after mechanical ventilation in the newborn. Critical Care Medicine 10: 361-362, 1982.

32. Robinson M, Maayan C, Eyal FG, Armon Y, Bar-Yishai E, Godfrey S: Does the pattern of ventilation determine the degree of lung damage following intensive care of the newborn? Israel Journal of Medical Sciences 18: 835-839, 1982.

33. Arad I, Maayan C, Eyal FG: The closure process of the ductus arteriosus. Harefuah 103: 131-133, 1982. (In Hebrew)

34. Sagi E, Alpan G. Eyal FG: Ultrasonic guidance of suprapubic aspiration in infants. Journal of Clinical Ultrasound 11: 347-348, 1983.

35. Arad I, Eyal FG: High plasma ascorbic acid level in premature neonates with intraventricular hemorrhage. American Journal of Diseases of Children 137: 949-951, 1983.

36. Weinstein D, Margalioth EJ, Navot D, Mor-Yoseph S, Eyal FG: Neonatal fetal death following cesarean section secondary to hyperextended head in breech presentation. Acta Obstetrica Gynecologica Scandinavica 62: 629-631, 1983.

37. Eyal FG, Arad I, Goder K, Robinson M: High frequency positive pressure ventilation in neonates. Critical Care Medicine 12: 793-797, 1984.

38. Sagi E, Eyal FG, Alpan G, Patz D, Arad I: Idiopathic apnea of prematurity treated with Doxapram and Aminophylline. Archives of Disease in Childhood 59: 281-283, 1984.

39. Alpan G, Eyal FG, Springer C, Glick B, Goder K, Armon J: Heparinization of alimentation solutions administered through peripheral veins in premature infants: A controlled study. Pediatrics 74: 375-378, 1984.

40. Alpan G. Eyal FG, Sagi E, Springer C, Patz D, Goder K: Doxapram in the treatment of idiopathic apnea of prematurity unresponsive to Aminophylline. Journal of Pediatrics 104: 634-636, 1984.

41. Linder N, Korman SH, Eyal FG, Michel J: Trimethoprim-sulfamethoxazole in neonatal Flavobacterium meningosepticum infection. Archives of Disease in Childhood 59: 582-584, 1084.

42. Maayan C, Peleg O, Eyal FG, Mogle P, Rosenmann E, Bar-Ziv B: Idiopathic infantile arterial calcification: A case report and review of the literature. European Journal of Pediatrics 142: 211-215, 1984.

43. Vinograd I, Udassin R, Arad I, Nissan S, Eyal FG: Outcome of major surgery in preterm infants weighing less than 1500 grams. Modern Problems in Pediatrics. Vol 23. Editor: S. Karger, Basel 1985, pp. 74-81.

44. Alpan G, Glick B, Peleg O, Amit Y, Eyal FG: Pneumothorax due to endotracheal tube suctioning. American Journal of Perinatology 1: 345-348, 1985.

45. Eyal FG, Alpan G, Sagi I, Glick B, Dgani I, Arad I: Aminophylline versus Doxapram in idiopathic apnea of prematurity. A double blind control study. Pediatrics 75: 709-713, 1985.

46. Glick B, Alpan G, Vinograd I, Udassin R, Moegle P, Eyal FG: Meconium plugs and intussusceptions in a premature infant. American Journal of Perinatology 2: 7-69, 1985.

47. Alpan G. Eyal FG, Vinograd I, Udassin R, Amir G, Mogle P, Glick B: Localized intestinal perforations following enteral administration of Indomethacin in premature infants. Journal of Pediatrics 106: 277-281, 1985.

48. Alpan G, Gottschalk S, Glick B, Eyal FG: Endocardial fibrosis and hydrops fetalis in a premature infant. Helvetica Paediatrica Acta 40: 69-73, 1985.

49. Alpan G, Goder K, Glick B, Peleg O, Eyal FG: Pneumopericardium during CPAP in respiratory distress syndrome. Critical Care Medicine 12: 1080-1081, 1985.

50. Eyal FG, Sagi E, Alpan G, Glick B, Arad I: Use of Doxapram versus Aminophylline in weaning premature infants from mechanical ventilation. Critical Care Medicine 13: 124-125, 1985.

51. Alpan G, Glick B, Peleg O, Springer C, Eyal FG: False diagnosis of persistent fetal circulation due to misplacement of umbilical artery catheter. Southern Medical Journal 78: 1002-1004, 1985.

52. Arad I, Dgani Y, Eyal FG: Vitamin E and Vitamin C plasma levels in premature infants following supplementation of Vitamin C. International Journal for Vitamin and Nutrition Research 55: 395-397, 1985.

53. Zamir O, Eyal FG, Lernau O, Nissan S: Bilateral congenital posterolateral diaphragmatic hernia. American Journal of Perinatology 3: 56-57, 1986.

54. Maayan C, Eyal FG, Mandelberg A, Sapoznikov D, Lewis BS: Effect of mechanical ventilation on left ventricular performance in premature infants with respiratory distress syndrome and benefit of volume loading. Critical Care Medicine 14: 858-860, 1986.

55. Eyal FG, Hayek Z, Armengol J, Jones RL: Comparison of high-frequency negative pressure oscillation with conventional mechanical ventilation in normal and saline lavaged cats. Critical Care Medicine 14: 724-729, 1986.

56. Arad I, Glick B, Dgani Y, Salpeter J, Eyal FG: The vitamin C status of formula fed preterm infants. Am J Perinat 3: 104-106, 1986.

57. Eyal FG, Hayek Z, Armengol J, Jones RL: High frequency chest wall compression in cats with normal lungs. Pediatric Research 21: 183-187, 1987.

58. Hayek Z, Ryan A, Eyal FG, Jones R, Armengol J, King G, Finer N: Comparison of high frequency chest wall compression with conventional mechanical ventilation in cats. Critical Care Medicine 15: 76-81, 1987.

59. Arad I, Bar-Yishai, Eyal FG, Gross S, Godfrey S: Lung function in infancy and childhood following neonatal intensive care. Pediatric Pulmonology 3: 29-33, 1987.

60. Zamir O, Goldberg M, Udassin R, Peleg O, Nissan S, Eyal FG: Idiopathic gastrointestinal perforation in the neonate. J Pediatric Surgery 23: 335-337, 1988.

61. Alpan G. Glick B, Peleg O, Eyal FG: Pseudotumor cerebri and coma in vitamin D dependent rickets. Clinical Pediatrics 30: 254-256, 1991.

62. Aranda JV, Lopes JM, Blanchard P, Eyal FG, Alpan G: Treatment of neonatal apnea. Neonatal Clinical Pharmacology and Therapeutics. Edited by Ryllance G, Harvey D, Aranda JV. Butterworth Heinemann, Oxford. pp 95-113, 1991.

63. Aranda JV, Lopes JM, Blanchard P, Eyal FG, Alpan G: Drug treatment of neonatal apnea. Pediatric Pharmacology. Edited by Yaffe SJ, Aranda JV. 2nd edition, W.B. Saunders Co, Philadelphia. pp 193-204, 1992.

64. Afifi AM, Rijhsinghani AB, Eyal FG: Hydrops fetalis associated with congenital myotonic dystrophy. Am J Obstet Gynecol 166: 929-930, 1992.

65. Langbaum M, Eyal FG: Stomacoccus Mucilaginosus septicemia and meningitis in a premature infant. Pediatric Infectious Dis J 11: 334-335, 1992.

66. Eyal FG: The small for gestation age preterm infant. Textbook of Prematurity: Antecedents, Treatment and Outcome. Edited by Witter FR, Keith L. Little, Brown and Co. pp 361-369, 1993.

67. Langbaum M, Eyal FG: A practical and reliable method of measuring blood pressure in the neonate by pulse oximetry. J of Pediatrics 10/94, pp. 591-595.

68. Eyal FG, Hatchey WE, Curtet-Eyal NL, Kellum FE, Alpan G: Effect of modulators of hypoxic pulmonary vasoconstriction on the response to inhaled nitric oxide in a neonatal model of severe pulmonary atelectasis. Seminars in Perinatology 20(3), 186-193, (June) 1996.

69. Hachey WE, Curtet-Eyal N, Kellum FE, Eyal FG: High frequency oscillatory ventilation vs. conventional ventilation in a piglet model of early meconium aspiration. Critical Care Medicine 26(3), pg. 556, March 1998.

70. Matthay MA, Bhatacharya S, Gaver D, Ware LB, Lim L, Syrkwa O, Eyal FG, Hubmayr R: Ventilator-Induced Lung Injury. American Journal of Physiology. In Press, 2002.

ABSTRACTS

1. Aranda JV, Mandelberg A, Beharry K, Rex J, Peleg O, Eyal FG: Metabolism of Doxapram in premature newborn. Pediatric Research 21:232A, 1987.

2. Peters J, Fraser C, Stuart S, Eyal FG, Baumgartner W, Robotham J: Negative intrathoracic pressures decreases mitral and aortic flow. Circulation 76, 1987.

3. Peleg O, Mandelberg A, Eyal FG: Increase pulmonary vascular resistance following the use of muscle relaxant in distressed neonates. Pediatric Research 23: 519A, 1988.

4. Cartaya E, Pathak A, Hamm CR Jr, Eyal FG: Efficacy and safety of Doxapram “made in U.S.A.” in the therapy of apnea of prematurity refractory to methylxanthine treatment. Pediatric Research 25, 1812A, 1989.

5. Hamm CR Jr, Cartaya E, Eyal FG: Determinants of FiO2 in oxygen supplementation by nasal cannulae. Pediatric Research 25, 1857A, 1989.

6. Hamm CR Jr, Eyal FG: Effect of high frequency chest wall vibration on gas exchange and lung function. Pediatric Research 25, 1858A, 1989.

7. Pathak A, Hamm CR Jr, Eyal FG, Walters K, Rijshinghani A, Bohlman M: Maternal vitamin K1 administration for prevention of intraventricular hemorrhage in preterm infants. Pediatric Research 27, 1299A, 1990.

8. Hamm CR Jr, Curtet-Eyal N, Eyal FG: Ventilation by high frequency chest wall vibration in saline lavaged rabbits. Pediatric Research 27, 1811A, 1990.

9. Hamm CR Jr, Millan J, Curtet-Eyal N, Eyal FG: High frequency jet ventilation preceded by lung volume recruitment decreases hyaline membrane formation in surfactant deficient lungs. Pediatric Research 27, 1812A, 1990.

10. Eyal FG, Chest F, Peleg O, Curtet-Eyal N, Celom F, Gabrielson E, Adler W: Exogenous surfactant treatment increases pulmonary leukostasis. Pediatric Research 31, 1821A, 1992.

11. Eyal FG, Peleg O, Hamm CR Jr, Curtet-Eyal N, Celom F, Gabrielson E: High frequency jet ventilation improves the response to surfactant replacement. Pediatric Research 31, 1822A, 1992.

12. Eyal FG, Peleg O, Hamm CR Jr, Curtet-Eyal N, Celom F, Gabrielson E: Exogenous surfactant treatment: Different surfactant preparations and different ventilatory strategies. Does it make a difference? Pediatric Research 33, 1925A, 1993.

13. Zayek MM, Coker PJ, Hamm CR Jr, Parker JC, Peevy KJ, Eyal FG: Endogenous and exogenous nitric oxide (NO) regulation of pulmonary hemodynamics and gas exchange in acute lung injury. Pediatric Research: Abstract #2126, 37(4), pt 2, April 1995.

14. Hachey WE, Curtet-Eyal N, Kellum F, Alpan G, Eyal FG: Indomethacin blunts the response to inhaled nitric oxide in a neonatal model of severe pulmonary atelectasis. Pediatric Research: Abstract #1989, 37(4), pt 2, April 1995.

15. Hachey WE, Curtet-Eyal N, Kellum FE, Alpan G, Eyal FG: Peripheral chemoreceptor agonists impair the improvement of oxygenation produced by inhaled nitric oxide in a neonatal model of severe pulmonary atelectasis. Pediatric Research: Abstract #1990, 37(4), pt 2, April 1995.

16. Langbaum ME, Curtet-Eyal N, Kellum FE, Eyal FG: Improved cardiovascular tolerance to mechanical ventilation by blockage of leukocyte adhesion molecules. Pediatric Research: Abstract #2019, 37(4), pt 2, April 1995.

17. Eyal FG, Hachey WE, Curtet-Eyal N, Alpan G: Effect of various modulators of hypoxic pulmonary vasoconstriction on the response to inhaled nitric oxide in a neonatal model of severe pulmonary atelectasis. 1995 International Perinatal Collegium.

18. Eyal FG, Hamm CR Jr, Zayek MM, O’Donnell K, Whitehurst RM Jr: Effect of inhaled nitric oxide (NO) and pH on pulmonary vascular resistance (PVR) in thromboxane induced pulmonary hypertension. Pediatric Research Abstract #1974, 39(4), pt 2, pg. 332A, April 1996.

19. Moore RB, Hamm CR Jr, O’Donnell K, Eyal FG: High airway pressure induced lung injury is not prevented by perfluorocarbon associated gas exchange. Pediatric Research Abstract #2037, 39(4), pt 2, pg. 342A, April 1996.

20. Bosarge P, Hamm CR Jr, Eyal FG: Combination of nitric oxide and Tolazoline reduces pulmonary vascular resistance better than either agent alone in oleic acid induced lung injury. Journal of Investigative Medicine, Vol. 45(1), pg. 69A, 1/97.

21. Eyal FG, Hamm CR Jr, Bosarge P, Beals DA, O’Donnell K: Synergy between inhaled nitric oxide and Tolazoline in pulmonary hypertension. International Perinatal Collegium, 1997.

22. Hamm CR Jr, Eyal FG, Bosarge P, O’Donnell K: Pulmonary vasodilation by nitric oxide and Tolazoline in pulmonary hypertension, with and without lung disease, in piglets. Pediatric Research 41(4), pt 2, Abstract #1513, pg. 255A, April 1997.

23. Eyal FG, Hamm CR Jr, Beals DA, O’Donnell K, Whitehurst RM Jr: Efficacy of inhaled nitric oxide (iNO) and alkalosis during partial liquid ventilation in pulmonary hypertension. Pediatric Research 41(4) pt 2, Abstract #1495, pg. 252A, April 1997.

24. Zayek MM, Hamm CR Jr, Whitehurst RM Jr, Eyal FG: Indomethacin (IND) does not blunt the response to inhaled nitric oxide (iNO) therapy in piglets with oleic acid lung injury (OALI). Pediatric Research 41(4) pt 2, Abstract #1120, pg. 189A, April 1997.

25. Beals DA, Bosarge PL, Hamm CR Jr, Eyal FG: Ventilation with perfluorocarbon vapor prevents secondary lung injury due to intestinal ischemia/reperfusion. Journal of Investigative Medicine 46(1), pg. 17A, January 1998.

26. Cave CB, Beals DA, Hamm CR Jr, Eyal FG: Partial liquid ventilation depresses cardiac output in piglets without parenchymal lung disease. Journal of Investigative Medicine 46(1), pg. 17A, January 1998.

27. Beals DA, Bosarge PL, Hamm CR Jr, Eyal FG: Ventilation with perfluorocarbon vapor prevents secondary lung injury due to intestinal ischemia/reperfusion. Critical Care Medicine 26(1), pg. A115 (Suppl), January 1998.

28. Hamm CR Jr, Beals DA, O’Donnell K, Zayek MM, Whitehurst RM Jr, Eyal FG: Pulmonary administration of prostacyclin (PGI2) during partial liquid ventilation (PLV) in an animal model of pulmonary hypertension (PHT). Pediatric Research 43(4) pt 2 of 2, Abstract #1662, pg. 284A, April 1998.

29. Hamm CR Jr, Beals DA, O’Donnell K, Zayek MM, Whitehurst RM Jr, Eyal FG: Inhaled nitric oxide (iNO) and inhaled prostacyclin (iPGI2) in an animal model of pulmonary hypertension (PHT): compared efficacy and synergy. Pediatric Research 43(4), pt 2 of 2, Abstract #1661, pg. 283A, April 1998.

30. Hamm CR Jr, Beals DA, Bosarge PL, Eyal FG: Perfluorocarbon vapor ventilation prevents secondary lung injury due to intestinal ischemia/reperfusion. Pediatric Research 43(4), pt 2 of 2, Abstract #200, pg. 37A, April 1998.

31. Repetto JE, Alpan G, Eyal FG, McHargue L: High dose dopamine for treatment of neonatal hypotension. Pediatric Research 43(4), pt 2 of 2, Abstract #1111, pg. 191A, April 1998.

32. Ramsey KM, Malone SG, Fey PD, Rupp ME, Glover B, Hamm CR Jr, Eyal FG: Aquaphor as a source of colonization and subsequent bloodstream infections among very low birthweight neonates. Submitted to The 8th Annual Meeting of The Society for Healthcare Epidemiology of America held in Orlando, Florida, April, 1998. Infection Control and Hospital Epidemiology 19(9), Abstract #53, pg. 689, 9/98.

33. Parker JC, Lausch RN, Yau XT, Eyal FG, Hamm CR Jr, Martin SL: High airway pressure stress induces cytokine release from perfused mouse lungs. Presented at The American Society of Mechanical Engineers Annual Summer Conference in Big Sky, Montana, July 1999.

34. Repetto JE, Eyal FG, McHargue L, Alpan G: High dose dopamine for the treatment of neonatal hypotension. Pediatric Research 45(4), part 2 of 2, Abstract #1297, pg. 221A, April 1999.

35. Hamm CR Jr, Krist KM, Coker-Flowers P, O’Donnell K, Zayek MM, Eyal FG: Respiratory failure secondary to barotrauma is effectively treated by exogenous surfactant or bronchoalveolar lavage with dilute surfactant. Pediatric Research 45(4), part 2 of 2, Abstract #1789, pg. 304A, April 1999.

36. Zayek MM, Hamm CR Jr, O’Donnell K, Coker-Flowers P, Eyal FG: Dopamine may not improve cerebral blood flow after cardiac depression secondary to intestinal ischemia-reperfusion injury. Pediatric Research 45(4), part 2 or 2, Abstract #1379, pg. 234A, April 1999.

37. Zayek MM, Hamm CR Jr, O’Donnell K, Eyal FG: Induced moderate hypothermia markedly exacerbates pulmonary hypertension and dysoxia in a neonatal piglet model of elevated pulmonary vascular resistance. Pediatric Research Supplement, 47(4), part 2 of 2, Abstract #2616, pg. 442A, April 2000.

38. Zayek MM, Hamm CR Jr, O’Donnell K, Eyal FG. Epinephrine is more effective than other sympathomimetics in correcting cerebral hypoperfusion associated with mesenteric ischemic reperfusion insult. Pediatric Research Supplement 47(4), part 2 of 2, Abstract #2617, pg. 442A, April 2000.

39. Zayek MM, Hamm CR Jr, O’Donnell K, Eyal FG: Induced moderate hypothermia markedly exacerbates pulmonary hypertension and dysoxia in a neonatal piglet model of elevated pulmonary vascular resistance. Accepted for Poster presentation at the 20th International Symposium on Intensive Care and Emergency Medicine held in Brussels, March 21-24, 2000. Crit Care 2000 4(suppl 1): S116-S117.

40. Zayek MM, Hamm CR Jr, O’Donnell K, Eyal FG: Epinephrine is more effective than other sympathomimetics in correcting cerebral hypoperfusion associated with mesenteric ischemic reperfusion insult. Accepted for Poster Presentation at the 20th International Symposium on Intensive Care and Emergency Medicine being held in Brussels, March 21-24 2000. Crit Care 2000, 4 (suppl 1): S28-S28 [Full Text]

41. Eyal FG, Hamm CR Jr, Coker-Flowers P, Stober M, Parker JC: The neutralization of alveolar macrophages delays and mitigates barotrauma-induced lung injury. Pediatric Research 49(4), part 2 of 2, Abstract #1543, pg. 270A, April 2001.

42. Zayek MM, Hamm CR Jr, Eyal FG, Stober M, Dean E: Effect of enteral glutamine supplement on intestinal permeability in premature infants. Pediatric Research 49(4), part 2 of 2, Abstract #1961, pg. 342A, April 2001.

43. Zayek MM, Hamm CR Jr, O’Donnell K, Eyal FG: Effect of moderate hypothermia on the cardiovascular response to hypoxia. Pediatric Research 49(4), part 2 of 2, Abstract #2167, pg. 378A, April 2001.

44. Eyal FG, Hamm CR Jr, Coker-Flowers P, Stober M, Parker JC. The neutralization of alveolar macrophages reduces barotrauma-induced lung injury. The FASEB Journal, 16(4), Abstract #367.12, pg. A410, March 2002.

45. Yoshikawa S, Parker JC, Sybert C, Eyal FG, Lausch RN: Ventilator induced lung albumin leak and MIP-2 production independent of TNF effect in intact mice. (Poster Presentation at 2002 American Thoracic Society Annual Meeting in Atlanta, GA). American Journal of Respiratory and Critical Care Medicine 165(8), pg. A787, April 2002.

46. Yoshikawa S, Sybert C, Eyal FG, Parker JC: Ventilator induced hyperpermeability in mouse lungs measured by an albumin ELISA. (Poster Presentation at Experimental Biology 2002 Annual Meeting). The FASEB Journal 16(4), Abstract #367.9, pg. A410, March 2002.

47. Parker JC, Yoshikawa S, Hamm CR Jr, Eyal FG. Enhanced gas exchange during alveolar flooding using a dual flow liquid ventilation system in piglets. (Poster Presentation by Dr. Parker at Experimental Biology 2002 Annual Meeting). The FASEB Journal 16(5), Abstract #652.4, pg. A876, March 2002.

48. Eyal FG, Hamm CR Jr, Coker-Flowers P, Stober M, Parker JC: Inhibition of macrophages with gadolinium chloride markedly attenuates the respiratory failure of the surfactant deficient lung. Pediatric Research 51 (4) Program Issue, Part 2 of 2, Abstract #2005, page 345A, April 2002.

49. Zayek MM, Estrada B, Hamm CR Jr, Eyal FG: Breast milk as a major source for “late onset” GBS infection in preterm infants. Pediatric Research 51 (4) Program Issue, Part 2 of 2, Abstract #1769, page 304A, April 2002.

50. Parker JC, Barnett TD, Hamm CR Jr, Eyal FG: Enhanced clearance of albumin solution from piglet lungs using tidal and bias flow liquid ventilation. Accepted for the American Thoracic Society 2002 Annual Meeting in Atlanta GA. Poster Presentation by Dr. Parker. American Journal of Respiratory and Critical Care Medicine 165(8), pg. A788, April 2002.

BOOKS

1. NEONATOLOGY – Basic Management, On-Call Problems, Diseases, Drugs. A LANGE clinical manual. Edited by Gomella TL, Cunningham MD. Consulting Editors: Eyal FG, O’Neal. W. Appleton & Lange, Norwalk, Connecticut, 1988.
2. NEONATOLOGY – Management, Procedures, On-Call Problems, Diseases, Drugs. A LANGE clinical manual. 2nd Edition. Edited by Gomella TL. Associate Editor: Cunningham MD. Consulting Editor: Eyal FG. W. Appleton & Lange, Norwalk, Connecticut, 1992.
3. NEONATOLOGY – Management, Procedures, On-Call Problems, Diseases, Drugs. A LANGE clinical manual. 3rd Edition. Edited by Gomella TL. Associate Editors: Cunningham MD, Eyal FG. W. Appleton & Lange, Norwalk, Connecticut, 1994.
4. NEONATOLOGY – Management, Procedures, On-Call Problems, Diseases, Drugs. A LANGE clinical manual. 4th Edition. Edited by Gomella TL. Consulting Editor: Eyal FG. Eyal Chapters entitled: (1) Thrombocytopenia and Platelet Dysfunction, (2) Temperature Regulation, and (3) Sedation & Analgesia. Appleton & Lange, Inc., Stamford, Connecticut, 1999.
5. NEONATOLOGY – Management, Procedures, On-Call Problems, Diseases, Drugs. A LANGE clinical manual. 5th Edition. (In Press)

ELECTRONIC PUBLICATIONS
Collaborating Author:
Eyal FG. Medscape Pediatrics Journal Scan. 2001; Vol 4, No. 7. (http://pediatrics.medscape.com/Medscape/features/JournalScan/
pediatrics/2001/js-ped0407.html)

RECENT PRESENTATIONS BEFORE PROFESSIONAL GROUPS

Pediatric Trends (16th Annual). “Erythropoietin Use in the Newborn”. Sponsored by Johns Hopkins Medical Institutions. Baltimore, Maryland, April 1989.

Pediatric Trends (17 Annual). “High Frequency Ventilation”. Sponsored by Johns Hopkins Medical Institutions. Baltimore, Maryland, April 1990.

Pediatric Trends (21st Annual). “Overview of New Treatment Modalities for Neonatal Respiratory Failure”. Sponsored by Johns Hopkins Medical Institutions, Baltimore, Maryland, April 11-16, 1994.

NANN Conference: The Evolution of Neonatal Care, Baltimore, Maryland. “In Search of the Magic Bullet: Strategies for the Prevention of IVH”. Lecture presented 3/18/95. Workshop: “HFIV & HFO: Results of Trials and Clinical Use” (3/19/95). Conference held March 16-19, 1995.

Alabama Society of Neonatology Annual Conference (1995): Two Days of Neonatology (1) Frontiers in Respiratory Technology (2) The Tiny Baby, IVH and Outcome. “Liquid Ventilation”. Sponsored by the University of South Alabama Division of Neonatology. Held in Guntersville, Alabama April 28-29, 1995.

International Perinatal Collegium Meeting. “Effect of Various Modulators of Hypoxic Pulmonary Vasoconstriction on the Response to Inhaled Nitric Oxide in a Neonatal Model of Severe Pulmonary Atelectasis”. Garderen, The Netherlands, July 22-27, 1995.

Alabama Society of Neonatology Annual Conference (1996): Advances in Neonatal Care. “Should We Use the Stomach More Frequently in the Extremely Low Birthweight Infant?” Held in Birmingham, Alabama April 1996.

XVth European Congress of Perinatal Medicine, Poster Presentation. “Changes in Acid Base Status Does Not Affect the Response to Inhaled Nitric Oxide”. Glasgow, Scotland, September 1996.

1997 Annual Meeting of the Pediatric Academic Societies’ (SPR). “Efficacy of Inhaled Nitric Oxide (iNO) and Alkalosis During Partial Liquid Ventilation in Pulmonary Hypertension.” (Poster Presentation) Washington DC, May 2 – 6, 1997.

Alabama Society of Neonatology Annual Conference (1997): Newborn Medicine for Pediatricians and Neonatologists: Common Medical and Legal Dilemmas. Lecture Title: “Hypothyroxinemia in the Very Low Birthweight Infant: Is It a Problem?” Orange Beach, Alabama, May 30 – June 1, 1997.

International Perinatal Collegium. “Synergy Between Inhaled Nitric Oxide and Tolazoline in Pulmonary Hypertension”. Mont Tremblant, Quebec, CANADA. July 18-22, 1997.

Mobile District Dietetic Association. “Nutrition for the Very-Low-Birthweight-Infant Problems”. September 17, 1997.

Pediatric Academic Societies’ (SPR) 1998 Annual Meeting (Poster Presentation). “Pulmonary Administration of Prostacyclin (PG12) during Partial Liquid Ventilation (PLV) in an Animal Model of Pulmonary Hypertension (PHT). New Orleans, LA May 1-5, 1998.

Pediatric Academic Societies’ (SPR) 1998 Annual Meeting (Poster Presentation). “Inhaled Nitric Oxide (iNO) and Inhaled Prostacyclin (iPGI2) in an Animal Model of Pulmonary Hypertension (PHT): Compared Efficacy and Synergy. New Orleans, LA May 1-5, 1998.

27th Respiratory Care Conference (Tristate) “Changing Times: A Continuation”. Topics: What is New in Neonatal Respiratory Care – Surfactant (Part 1) and High Frequency Ventilation (Part 2). August 5-8, 1998 at the Grand Casino Biloxi Bayview Hotel in Biloxi, MS.

Pediatric Academic Societies’ (SPR) 1999 Annual Meeting (Poster Presentation). “Respiratory Failure Secondary to Barotrauma is Effectively Treated by Exogenous Surfactant of Bronchoalveolar Lavage with Dilute Surfactant”. May 1-4 1999, San Francisco, CA.

Alabama Society of Neonatology Annual Conference (1999): 2 Lectures: “Respiratory Care Issues of the Newborn I” and Respiratory Care Issues of the Newborn II – Hot Topics”. June 3-4, 1999 in Montgomery, AL.

Methodist Hospital, Memphis, Tennessee. Grand Rounds Presentation: “Exogenous Surfactants in the Management of RDS”. March 8, 2000. Methodist Hospital Continuing Medical Education - supported by Forest Laboratories, Inc.

Sacred Heart Hospital, Pensacola, Florida. Grand Rounds Presentation: “Exogenous Surfactants in the Management of RDS”. Supported by Forest Laboratories, Inc.

Providence Hospital OBGYN Conference, Mobile, AL. “Risk of RDS Babies Born Prior to 39 Weeks”. July 11, 2000.

National Association of Neonatal Nurses (NANN) 16th National Meeting. “Exogenous Surfactants in the Management of RDS”. San Antonio Convention Center, San Antonio, Texas. 10/1/00.

Atmore Community Hospital (Atmore, AL), Monroe County Hospital (Monroeville, AL) and DW McMillan Hospital (Brewton, AL). Conference lecture with reference to Pneumothorax, Chest Tube Placement and Pneumothorax Radiology Films. November 2, 2000 in Atmore.

Louisiana State University Neonatology Conference. “Exogenous Surfactants in the Management of RDS”. Presented to group of Neonatologists, Respiratory Therapists and Nurse Practitioners. Shreveport, LA November 21, 2000. (Supported by Forest Laboratories, Inc.)

Phoebe Putney Memorial Hospital, Albany, Georgia. “Exogenous Surfactants in the Management of RDS”. Lecture presented to Respiratory Therapists and Neonatologists. February 23, 2001. (Supported by Forest Laboratories, Inc.)

Alabama State Perinatal Conference. “Neonatal Neurological Outcomes’. Gulf Shores, AL March 30-31, 2001.

Pediatric Academic Societies’ (SPR) 2001 Annual Meeting. Poster Presentation: “The Neutralization of Alveolar Macrophages Delays and Mitigates Barotrauma-Induced Lung Injury”. Baltimore Convention Center in Baltimore, MD April 28 – May 1, 2001.

University of South Alabama Department of Obstetrics and Gynecology: “Extreme Prematurity”. OBGYN Grand Rounds 12/13/01.

Experimental Biology 2002 “Translating the Genome”. Poster and Oral Presentation: “The Neutralization of Alveolar Macrophages Reduces Barotrauma-Induced Lung Injury”. New Orleans, LA. April 20-24, 2002.

Pediatric Academic Societies’ (SPR) 2002 Annual Meeting. Poster Presentation. “Inhibition of Macrophages with Gadolinium Chloride Markedly Attenuates the Respiratory Failure of the Surfactant Deficient Lung”. Baltimore Convention Center in Baltimore, MD May 4-7, 2002.

Pediatric Academic Societies’ (SPR 2002 Annual Meeting. Poster Presentation. “Breast Milk as a Major Source for “Late onset” GBS Infection in Preterm Infants”. Baltimore Convention Center in Baltimore, MD May 4-7, 2002.
 

The International Meeting about Hot Topics in Neonatology. “The Safety of Mild Therapeutic Hypothermia”. Invited speaker on behalf of the University Henri Poincare from Nancy, France. October 5, 2002 in Nancy, France.
 

UNIVERSITY OF SOUTH ALABAMA INSTITUTIONAL REVIEW BOARD (IRB)

Assistant Investigator
“Neutrophil Gene Expression in Premature Infants with Bronchopulmonary Dysplasia
and Periventricular Leukomalacia”
Protocol No. 01-277
2002 (1 year approval)
 

PAST EXTRAMURAL GRANT SUPPORT

National Institute of Health: National Heart, Lung and Blood Institute
Co-Investigator (Principle Investigator Dr. James C. Parker, USA Dept. of Physiology)
“Airway Perfusion Assisted Liquid Ventilation”
1 year/phase (1999-2000)
$105,000
 

PRESENT EXTRAMURAL SUPPORT

***A Multicenter, Randomized, Controlled Trial Comparing the Safety and Effectiveness of Bronchoalveolar Lavage with Surfaxin to Standard Care for the Treatment of Meconium Aspiration Syndrome (MAS) in Newborn Infants. 
Running Title: Surfaxin vs. Standard Care in MAS 
Principal Investigator
IND#40,287
$3000 per patient for standard care, $4000 per patient randomized to study drug, and $500 per patient for follow-up.
Sponsored by Discovery Laboratories (1999 – Present)

***Infasurf Survanta Comparison Project 2000 (ISCP 2000)
Comparing the efficacy and safety of Survanta and Infasurf in the prevention and treatment of respiratory distress syndrome in low birthweight infants.
Sponsored by a grant from Forest laboratories, Inc. to Pediatrix Medical Group, Inc.
$300.00 per Infant
October 2001 – Present

***Growth and Tolerance in Premature Infants Fed Mother’s Milk
Supplemented with Human Milk Fortifiers
Sponsored by Mead Johnson Nutritionals
$2700.00 per Infant
January 2002 – Present
 

PRESENT INTRAMURAL SUPPORT

University of South Alabama College of Medicine
2002 Children’s Research Grant
Principle Investigator
“Are Macrophages Involved in the Development of Lung Injury Following Surfactant Depletion and Mechanical Ventilation?”
$12,000 for calendar year 2002 (possible renewal for 1 addition year contingent upon progress report)
 

PAST INTRAMURAL SUPPORT
University of South Alabama College of Medicine
1999 Children’s Research Fund Grant
Co-Investigator
“Effect of Enteral Glutamine on Intestinal Permeability in the Very Low Birthweight Infant”
$10,000 (1 year)

University of South Alabama College of Medicine
1999 Children’s Research Fund Grant
Co-Investigator
“Serum Amyloid A Concentrations in Neonates Evaluated for Sepsis”
$10,000 (1 year)

SPEAKERS PROGRAM SUPPORT
“Exogenous Surfactants in the Management of RDS”
Speakers Program sponsored by Forest Laboratories, Inc.
(Designed to educate Neonatologists and others i.e. respiratory therapists, nursing personnel, who provide neonatal care on the latest trends and treatment in Respiratory Distress Syndrome. (10/99 – Present)
 

ON-GOING RESEARCH AND CLINICAL STUDIES
***Gentamicin Study (Dr. Eyal and Dr. Zayek - Current study at USA Children’s & Women’s Hospital)

***Vancomycin Study (Dr. Eyal - current study at USA Children’s & Women’s Hospital)

***Perforation Study (Looking at spontaneous perforations vs. NEC)
(Dr. Eyal - current study at USA Children’s & Women’s Hospital)