Brian William Fouty, M.D.
Associate Professor
Phone: (251) 460-7218
bfouty@jaguar1.usouthal.edu

EDUCATION

O'Dea High School, Seattle, Washington, 1979.
 

Stanford University, Palo Alto, California.
      B.S. June, 1983.
 

University of Washington Medical School, Seattle, Washington.
      M.D. June, 1988.

POST-DOCTORAL TRAINING

University of Arizona Health Sciences Center, Tucson, Arizona.
Residency, Internal Medicine. July, 1988- June, 1991.
 

National Heart and Lung Institute, Brompton Hospital, London, England.
Interstitial Lung Disease Unit. November, 1990- January, 1991.
 

University of Washington, Seattle, Washington. 
Biophysical and Molecular Analysis of Marine Invertebrates. May- June, 1994.
 

University of Colorado Health Sciences Center, Denver, Colorado.
Pulmonary and Critical Care Fellowship. July, 1992- June, 1996.
 

WORK EXPERIENCE

Associate Professor: University of South Alabama College of Medicine, Mobile, Alabama. March, 2004 to present.
 

Assistant Professor: University of Colorado Health Sciences Center, Denver, Colorado. July, 1996 to February, 2004.
 

Attending Physician: Denver Public Health Department, Denver, Colorado. 
October, 1994 to February, 2004.
 

Attending Physician: National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado. November, 1993 to January, 1995.
 

Attending Physician: Indian Health Service, Pine Ridge, South Dakota; Eagle Butte, South Dakota; Belcourt, North Dakota. December, 1991- June, 1992.
 

Attending Physician: Kanakanak Indian Health Service Hospital, Dillingham, Alaska. 
July, 1991- December, 1991. 
 

BOARD CERTIFICATION

American Board of Medical Examiners, April, 1989.
 

American Board of Internal Medicine, September, 1991.
- Recertification: November, 2001.
 

American Board of Internal Medicine, Pulmonary Disease Subspecialty Boards, November, 1994.
 

American Board of Internal Medicine, Critical Care Subspecialty Boards,
November, 1995.
 

PROFESSIONAL SOCIETIES

American Thoracic Society
American Federation of Clinical Researchers
 

AWARDS

• K08 Mentored Clinician Scientist Award, National Institutes of Health. Activation July, 1996.
• Howard Hughes Medical Investigator Award (1 year award).     Activation January, 1999.
• Beginning Grant-in-Aid, American Heart Association. Activation July, 1999.
• Clinician Scientist Award, American Heart Association. January, 1996. (declined)
• Postdoctoral Fellow Award for Excellence in Research, Western Section of American Federation of Clinical Researchers. 1995.
• Excellence in Teaching. University of Colorado School of Medicine. 2003
• Excellence in Teaching. University of Colorado School of Medicine. 2001 
• Excellence in Teaching. University of Colorado School of Medicine. 1999
• Excellence in Teaching. University of Colorado School of Medicine. 1998
 

PUBLICATIONS

• Fouty BW and Rodman DM. Mevastatin can induce G1 arrest and apoptosis in pulmonary artery smooth muscle cells independent of p27. Circulation Research. 2003 March 21;92(5):501-9.
 
• Fouty BW, Grimison B, Fagan KA, Le Cras TD, Harrall, JW, Miller-Hoedt M, Sclafani RA, Rodman DM. p27^Kip1 is important in modulating pulmonary artery smooth muscle cell proliferation. Am J Resp Cell Mol Bio. 2001 Nov 1;25(5):652-658.
 
• Fouty BW, Lynch DA, Fontenot AP, Schwarz MI. Hypoxemia explained 36 years later. Chest. 2001 Nov;120(5):1739-41.
 
• Maloney JP, Halbower AC, Fouty BW, Fagan KA, Balasubramaniam V, Pike AW, Fennessey PV, Moss M.Systemic absorption of food dye in patients with sepsis. N Engl J Med. 2000 Oct 5;343(14):1047-8.
  
• Fouty BW and Rodman DM. Pulmonary vascular gene transfer. Prospects for successful therapy for pulmonary hypertension. Am J Respir Cell Mol Biol. 1999;21: 555-557.
 
• Li KX, Fouty B, McMurtry IF, and Rodman DM. Enhanced ETa-receptor-mediated inhibition of Kv channels in hypoxic hypertensive rat pulmonary artery myocytes. Am J Phys. 1999;46:H363-370.
 
• Fagan KA, Fouty BW, Tyler RC, Morris KG Jr, Hepler LK, Sato K, LeCras TD, Abman SH, Weinberger HD, Huang PL, McMurtry IF, Rodman DM. The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia. J Clin Invest 1999 Jan;103(2):291-9
 
• Fagan KA, Tyler RC, Sato K, Fouty BW, Morris KG Jr, Huang PL, McMurtry IF, Rodman DM. Relative contributions of endothelial, inducible, and neuronal NOS to tone in the murine pulmonary circulation. Am J Physiol 1999 Sep;277(3 Pt 1):L472-8 
 
• Fouty B, Frerman F, and Reves R. Riboflavin to treat nucleoside analogue-induced lactic acidosis. Lancet. 1998;352: 291-292.
 
• Fouty B, Muramatsu M, Cohen A, Komalavilas P, McMurtry IF, Lincoln T, and Rodman DM. Protein kinase G is not essential to cGMP-mediated vasodilation in the hypertensive pulmonary circulation. Am. J. Phys. (Heart Circ. Physiol.) 1998; 274:H672-H678).
 
• Stevens, B. Fouty, L. Hepler, D. Richardson, G. Brough, I. F. McMurtry & D. M. Rodman. Cytosolic Ca²⁺ and adenylyl cyclase responses in phenotypically distinct pulmonary endothelial cells. Am J Physiol. 1997; 272: L51-L59.
 
• Cohen A, Hanson K, Morris K, Fouty B, McMurtry IF, Clarke W, and Rodman DM. Inhibition of cGMP-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats. J Clin Invest. 1996; 97: 172-179. 
 
• Stevens T, Fouty B, Cornfield D, and Rodman DM. Reduced P02 alters the behavior of Fura-2 and Indo-1 in bovine pulmonary artery endothelial cells. Cell Calcium. 1994; 16 (5): 404-412.
 
• Fouty B, Pomeranz M, Thigpen T, and Martin R. Dilatation of bronchial stenoses due to sarcoidosis using a flexible fiberoptic bronchoscope. Chest. 1994;106(3): 677-681. 
 
• Vedder N, Fouty B, Winn R, Harlan J, and Rice C. Role of neutrophils in generalized reperfusion injury associated with resuscitation from shock. Surgery. 1989; 106(3): 509-516.
 

RESEARCH SUPPORT

Active
“Heterogeneous Neutrophil Responses in Acute Lung Injury”
Principal Investigator: Edward Abraham, M.D.; Agency: NIH/NHLBI
Type: Program Project Grant: July 1, 2002- June 30, 2007
Goals: To study the role of neutrophil responses in development of acute lung injury.
Role: Co-Investigator
 

“Control of Cell Cycle and Proliferation in Tsc2-/- mice”
Principal Investigator: Brian Fouty MD; Agency: LAM Foundation.
Type: Established Investigator Award; July 2002- June, 2004.
Goals: This award studies the mechanisms that produce abnormal cellular proliferation in the absence of the tumor suppressor gene Tsc2.
Role: Principal Investigator.
 

Pending
Cell Cycle Regulation of Pulmonary Vascular Remodeling
Principal Investigator: Brian Fouty, MD; Agency NIH/NHLBI
Type: RO1
Goals: To study how cdk inhibitors modulate pulmonary vascular remodeling.
Role: Principal Investigator.
 

    Completed

NO/cGMP Relaxation in the Pulmonary Circulation.
Principal Investigator: Brian Fouty MD; Agency: NIH/NHLBI
Type: KO8; July 1996- June 2001.
Goals: Proposal looks at the mechanisms through which NO causes pulmonary vasodilation.
Role: Principal Investigator.

“Role of KIP1/CIP1 Cyclin Dependent Kinase Inhibitors in the Development of Pulmonary Hypertension”
Principal Investigator: Brian Fouty, MD; Agency: American Heart Association.
Type: Beginning Grant in Aid; July 1999 to June 2002.
Goals: Examine the role of the cdk inhibitors in controlling pulmonary vascular remodeling.
Role: Principal Investigator.