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    NIH - Funded Training in Cell Signaling & Lung Pathobiology
    		 
       
     

    Wiltz Walker Wagner, Jr., Ph.D.
    Phone: (251) 460-6198
    Fax: (251) 460-6798
    wwwagner@jaguar1.usouthal.edu
       
    EDUCATION
     

    Ph.D. in Physiology and Biophysics, Colorado State University, 1974

       
    PROFESSIONAL EXPERIENCE
     
    1960‑1974 Research Associate, University of Colorado Medical School
    1972‑1985 Faculty, NIH Training Grant, University of Colorado Medical School
    1974‑1980 Instructor in Medicine, University of Colorado Health Sciences Center
    1980‑1985 Assistant Professor of Medicine, University of Colorado Medical School
    1981‑1985  Graduate Faculty, University of Colorado
    1982‑1985  Assistant Director, CVP Laboratory, University of Colorado Medical Center
    1985-1990 Associate Professor, Anesthesiology and Physiology, Indiana University Medical School
    1985‑2005 Director of Research, Anesthesia Department, Indiana University Medical School
    1986‑2005 Graduate Faculty, Indiana University
    1989-1990 V.K. Stoelting Distinguished Investigator, Indiana University School of Medicine
    1990-2005 EmeritusV.K.Stoelting Professor of Anesthesiology, Indiana University School of Medicine
    1990-2005 Emeritus Professor of Physiology and Biophysics, Indiana University School of Medicine
    1991-2005  Emeritus Professor of Pediatrics, Indiana University School of Medicine
    2005-date Professor of Pharmacology, University of South Alabama
       

    MAJOR RESEARCH INTERESTS
     

    Control of the pulmonary circulation
    Pulmonary gas exchange
    Pulmonary pathophysiology of neutrophils
    Collateral ventilation
    History of medicine
    Comparative physiology of high altitude    
       
    PROFESSIONAL SOCIETIES
     

    American Society of Anesthesiologists
    American Thoracic Society (board 1999 - 2003)
    Biomedical Engineering Society
    European Respiratory Society
    Fellow, American Heart Association, Cardiopulmonary Council
    Fellow, American Physiological Society, Cardiovascular Section
    International Anesthesia Research Society
    Microcirculatory Society
    New York Academy of Sciences
    Society of the Sigma Xi           

     

            
    PROFESSIONAL SERVICES
     

    Reviewer for the following journals: Journal of Applied Physiology (editorial board 1995-1999), American Review of Respiratory Diseases, American Journal of Physiology, Science, Circulation Research, Journal of Clinical Investigation, Journal of Physiology, American Journal of Pathology, Journal of Laboratory and Clinical Investigation, Microvascular Research, Microcirculation, Chest, Lung, Medicine and Science in Sports, American Journal of Respiratory and Critical Care Medicine, Journal of Vascular Research, Annals of Bioengineering, Respiratory Physiology & Neurobiology.
       
      Recent Study Sections:
     

    Cardiovascular A Study Section, NIH, ad hoc 1990.
    Respiratory and Applied Physiology Study Section, NIH, ad hoc 1993.
    Medical Research Council of Canada, ad hoc 1993, 1995, 1998.
    Veterans Administration Merit Review, ad hoc 1993.
    Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, ad hoc 1994, 1998
    Special Consultant, Aerospace Medicine Board, NASA, 1998
    John Simon Guggenheim Memorial Foundation, fellowship evaluation, ad hoc 1998.
    Small Business Innovation Research Study Section, Center for Scientific Review, NIH, 2000.
    Parker B. Francis Foundation, fellowship evaluation, ad hoc, 2000.
    RIBT Study Section, ad hoc, NIH, 2006
       
     

    Recent Conference Organizations:
    Advisory Committee, 4th International Symposium on High Altitude Medical Science, Matsumoto, Japan, 1991.
    Chairman, Fifth Grover Conference, The Pulmonary Circulation and Gas Exchange, Deckers, Colorado, 1991.
    Steering Committee, The Grover Conference, 1990 - present.
    Steering Committee, Mechanisms of Hypoxia Pulmonary Vasoconstriction, Matsumoto, Japan, 1991.
    Program Committee, Assembly on Pulmonary Circulation, American Thoracic Society, 1993 - present.
    Chairman, Pulmonary Circulation Assembly Program Committee, American Thoracic Society, 1994 - 1997
    Chairman, Pulmonary Circulation Assembly, American Thoracic Society, 1999 – 2003
    Executive Committee, Pulmonary Circulation Assembly, American Thoracic Society, 1999 – present
    Planning Committee, Pulmonary Circulation Assembly, American Thoracic Society, 1999 -- present
    Board of Directors, American Thoracic Society, 1999 - 2003.
    American Thoracic Society Assembly Structure Task Force, 2000.
    Pulmonary Circulation Foundation, Treasurer, 1999-present.
    Strategic Planning Committee, American Thoracic Society, 2003-2005.
       
    HONORS AND AWARDS
     
    1966  Honors Achievement Award, The Angiology Research Foundation
    1979 Lectures in Physiology and Medicine, Harvard Medical School, Boston
    1989  Glaxo Visiting Professor, University of British Columbia Medical School, Vancouver
    1990   Distinguished Scientist Lecturer, University of South Alabama, Physiology Department, Mobile
    1990 V.K. Stoelting Professor of Anesthesiology, Indiana University School of Medicine
    1990    Alliance of Distinguished Ranked Professors, Indiana University School of Medicine
    1994  Chairman, Pulmonary Circulation Assembly Program Committee, American Thoracic Society
    1999  Chairman, Pulmonary Circulation Assembly, American Thoracic Society (1999-2003)
    1999 Board of Directors, American Thoracic Society  (1999-2003)
    2000 Estelle Grover Lecturer, American Heart Association
    2002   After dinner speaker, Respiratory Section Dinner, American Physiological Society, New Orleans
    2003  Inaugural Fellow, Council on Cardiopulmonary, American Heart Association.
    2004 Robert F. Grover Prize, American Thoracic Society
    2005  Leadership Award, Pulmonary Circulation Assembly, American Thoracic Society
     


    TEACHING EXPERIENCE
      Major Visiting Lectureships/Professorships
     
    1969   Duke University, Department of Medicine, Durham, NC
    1970 University of California Medical School, Cardiovascular Research Institute, San Francisco, CA
    1972  University of Southern California Medical School, Los Angeles, CA
    1974 University of California Medical School, Department of Medicine, La Jolla, CA
    1979 University of California Medical School, Cardiovascular Research Institute, San Francisco, CA
    1979 Harvard Medical School, Department of Medicine, Boston, MA
    1981 Colorado State University, Department of Physiology, Fort Collins, CO
    1984 Medical College of Wisconsin, Department of Physiology, Milwaukee, WI
    1984  Harvard Medical School, Department of Medicine, Boston, MA
    1987 Université de Paris ‑ Sud, School of Medicine, Paris, France
    1987 Royal Postgraduate Medical School, University of London, London, England
    1987 Washington University School of Medicine, Department of Medicine, St. Louis, MO
    1988 University of Virginia Medical School, Department of Bioengineering, Charlottesville, VA
    1988 Pennsylvania State University Medical School, Department of Medicine, Hershey, PA
    1988 University of Kentucky Medical School, Division of Pharmacology, Lexington, KY
    1988 Université de Paris ‑ Sud, School of Medicine, Paris, France
    1988 Royal Postgraduate Medical School, University of London, London, England
    1988 Institut für Anaesthesiologie der Universität Erlangen-Nürnberg, Erlangen, West Germany
    1989 University of Washington School of Medicine, Department of Medicine, Seattle, WA
    1989 University of British Columbia Medical School, Vancouver, British Columbia, Canada
    1989  Écolé Normale Supérieure, Laboratoire de Physique, Paris, France
    1989  Instituto Boliviano de Biología de Altura, La Paz, Bolivia
    1989  Colegio Medico de Santa Cruz, Santa Cruz, Bolivia
    1989  Ludwig-Maximilians-Universität, München, West Germany
    1990 University of Washington School of Medicine, Bioengineering Department, Seattle WA
    1990 University of South Alabama, Physiology Department, Distinguish Scientist Lecture, Mobile, AL
    1991 Baylor Medical School, Leukocyte Biology Department, Houston, TX
    1991 Chiba University School of Medicine, Department of Chest Medicine, Chiba, Japan
    1991  National Cardiovascular Research Institute, Osaka, Japan
    1991  Colorado State University, Department of Physiology, Fort Collins, CO
    1992 NASA/Johnson Space Center, Division of Medical Sciences, Houston, TX
    1992 Guthrie Research Foundation, Sayre, PA
    1992 University of Texas Health Center, Tyler, TX
    1992 University of Utah, Pediatrics Department, Salt Lake City, UT
    1993 University of Minnesota, Department of Medicine, Minneapolis, MN
    1993 University of Cincinnati, Department of Anatomy and Cellular Biology, Cincinnati, OH
    1995 Harvard School of Public Health, Department of Physiology, Boston MA
    1995 Massachusetts Institute of Technology, Department of Fluid Mechanics, Boston, MA
    1996 Tulane University Medical School, Department of Pharmacology, New Orleans, LA
    1996 University of Colorado Medical School, Cardiovascular Pulmonary Laboratory, Denver, CO
    1996 University of South Alabama, Pharmacology Department, Mobile, AL
    1996 Colorado College, Biology Department, Colorado Springs, CO
    1997  Vascular Biology Center, Medical College of Georgia, Augusta, GA
    1998 University of California Medical School, Cardiovascular Research Institute, San Francisco, CA
    1999 Columbia College of Physicians and Surgeons, New York, NY
    1999 Brown University College of Medicine, Providence, RI
    1999 Harvard Medical School, Department of Medicine, Boston, MA
    1999 Johns Hopkins Medical School, Pulmonary Division, Baltimore MD
    2000 University of Pennsylvania, Institute for Environmental Medicine, Philadelphia, PA
    2001 Université de Paris ‑ Est, School of Medicine, Paris, France
    2001 University of Washington, Department of Medicine, Seattle, WA
    2002 University of Washington, Department of Medicine, Seattle, WA
    2003   University of Minnesota, Department of Medicine, Minneapolis, MN
    2003 Medical College of Wisconsin, Christopher Dawson Memorial Symposium, Milwaukee, WI
     

     
      Courses  Indiana
     

    F 735  Respiratory Physiology Seminar, Course Director, 1987, 1990
    F 702  Seminar in Physiology, 1986-1989, 1995-2006
    F 509  Respiratory Physiology in Dental Physiology Course, 1987- 2005
    F 513  Respiratory Physiology in Medical Physiology, 1988
    F 513  Medical Physiology - Problem Based Learning, 1993-2000
    Pulmonary and Critical Care Fellows Pulmonary Physiology, 1997, 1999, 2000, 2003
       
      Alabama  Courses
      IDL 590 – Special Topics – 2007
    IDL 630 –  Lung Biology – Course Director  2006 – present
    IDL 650 – Special Topics – Historical Figures in Pulmonary Research -- 2007
       
      Graduate Student Research Committee Chairman: Colorado: C.B. Feicht, M.S., 1979,  C.F. Sanborn, Ph.D., 1983,  S.M. Brooks, M.S. 1983,  J.M. Berning, M.S., Indiana: 1985, J.P. Bartek, M.S., M.D., 1987,  L.L. Checkley, M.D., Ph.D., 1992,  C.J. Warner, M.S., M.D., 1992, A.M. Lindeman, M.S., 1998,  E.M. Jaryszak, M.S., 2000, D. Sines, M.S. 2002, E.M. Jaryszak, M.D., Ph.D.2003
       
     

    Research Committee Member/Mentor: J.W. Barnard, Ph.D., 1987,  J.C. Falcone, Ph.D., 1988,  J.M. Steenbergen, Ph.D., 1993,  D.M. Walker, Ph.D., 1998, Y.M. Kobayashi, Ph.D., 1999, B.T. Weinzapfel, M.D., Ph.D. 2000, M.D.,  B. Zani, Ph.D. 2005
       
      Post‑Doctoral Research Fellows
     

    S. I. Rounds, M.D., 1975-1976; faculty at Brown University College of Medicine
    J.H. Newman, M.D., 1975-1976; faculty at Vanderbilt Medical Center
    G.J.  Redding, M.D.  1976-1977, faculty at University of Washington
    M.C. Hammill, M.D., 1976‑1977; faculty at Mayo Clinic
    T.S. Johnson, M.D., 1976‑1977; faculty at Harvard Medical School
    M.N. Gillespie, Ph.D., 1981‑1982; chairman at University of South Alabama
    M.D. Petrun, M.D., 1982‑1983; private practice, Ft. Collins
    D.F. Boggs, Ph.D., 1983‑1985; faculty at University of Montana
    S.A. Gebb, Ph.D., 1993-1994; faculty at University of South Alabama

       
      Anesthesia, Surgical, and Pediatric Clinician Scientists
     

    J. D. Emhardt, M.D., 1986‑1987; faculty at Indiana University  
    L. J. Means, M.D., 1986‑1987; faculty at Indiana University 
    P. M. McCormick, M.D., 1987; private practice, Minneapolis
    R. G. Presson, M.D., 1987-1988; faculty at Indiana University
    T. N. Harwood, M.D., 1988-1989; faculty at Bowman Gray Medical School
    M. C. Yoder, M.D., 1988-1990; faculty at Indiana University
    S. C. Hillier, M.D., 1989-1990; faculty at Indiana University
    K. O. Mounts, M.D., 1990-1991; faculty at Medical College of Wisconsin
    S. G. Walker, M.D., 1997-1999; faculty at Indiana University
    P.    Urusopone, M.D., 1999; faculty of Medicine, Chulalongkorn University, Bangkok
    M.D. Rodefeld, M.D. 2004; faculty at Indiana University School of Medicine
       
      Sabbatical Fellows
      R. L. Capen, Ph.D., 1977‑1978, 1984-1986, 1992-1993; Biology Chairman at The Colorado College
    T. Kuriyama, M.D., 1978‑1980; Pulmonary Chairman at Chiba University Medical School, Japan
    T. Sugita, M.D., Ph.D., 1980‑1982; faculty at Chiba University Medical School, Japan
    P. A. Hervé, M.D., 1986; faculty at the University of Paris
    O. Okada, M.D., 1989-1991; faculty at Chiba University Medical School, Japan
    N. Tanabe, M.D., 1994-1996; faculty at Chiba University, Japan
    J. Aono, M.D., 1995-1996; faculty at Kochi Medical School, Japan.
       
     

    Indiana University Administrative Duties
      Physiology Graduate Committee, 1996-1999
    Physiology Faculty Meeting Moderator, 1996-2003
    Chairman Education Committee, NIH training grant "Lung Pathophysiology," 1997-2003
    Salary Equity Panel, 1999
    Search Committee for Pulmonary Division Chief, 2001
    Search Committee for Anesthesia Chairman, 2002
       
    MAJOR RESEARCH GRANTS
     

    "The Effect of Hypoxia on the Pulmonary Vessels," National Science Foundation, Co‑Principal, 1963‑1969           150,000

    "The Effect of Hypoxia on the Pulmonary Vessels," U.S. Army Medical R&D Command, Principal, 1967-1972                 124,000

    "Pulmonary Circulatory Response to Hypoxia," National Institutes of Health RO1, Principal, 1971‑1973                          80,578

    "Program Project Grant; Project C: Pulmonary Microcirculation," National Institutes of Health, Principal, 1972‑1982      712,000

    "Athletic Amenorrhea," National Institutes of Health, Principal, 1981‑1984                                                                 256,000

    "Program Project Grant; Project C‑V: Collateral Ventilation," National Institutes of Health, Principal, 1982‑1985       162,000

    "Pulmonary Microcirculatory Hemodynamics," National Institutes of Health RO1, Principal, 1983‑2007                            3,400,000

    "Skeletal Integrity of Amenorrheic Runners," National Dairy Council, Principal, 1984‑1985                                    38,000

    "Special Fellowship" for R. L. Capen, National Institutes of Health, Sponsor, 1985‑1986                                                  27,000

    "Pulmonary Circulatory Transport Functions," American Heart Association, Indiana Affiliate, Principal, 1985‑1986           28,000

    "Hemodynamics of the Pulmonary Microcirculation," Indiana University Research Grant, Principal, 1986-1987            12,800

    "Almitrine et Circulation Capillaire Pulmonary," Servier Laboratories, Co-Principal, 1987‑1990                                     105,000

    "Hormone Profiles in Amenorrheic Runners," Methodist Research Foundation, Co-Principal, 1987-1988                         15,000

    "Pathophysiology of Lung Vascular Injury,"  National Institutes of Health RO1, Co-Principal, 1986‑1991                        676,766

    "Pulmonary Microcirculation in Perinatal Lambs," American Society of Anesthesiologists, Co-Principal, 1988-1989      15,000

    "The Fate of Gas Emboli in Pulmonary Circulation," International Anesthesia Research Grant, Co-Principal, 1988-1989        25,000

    "Effect of Almitrine on Pulmonary Microcirculation," International Anesthesia Research Grant, Co-Principal, 1989                 25,000

    "Pulmonary Microcirculation in Perinatal Lambs," Riley Memorial Association, Co-Principal, 1988-1989                                  18,300

    "The Fate of Gas Emboli in the Pulmonary Circulation," Indiana University Research Grant, Co-Principal, 1989-1990          18,000

    "The Pulmonary Circulation and Gas Exchange," National Institutes of Health, Principal, 1991-1992                             10,000

    "The Pulmonary Circulation and Gas Exchange," American Heart Association Grant, Principal, 1991-1992                              15,000

    "Mechanisms of Neutrophil Margination in the Normal Lung," National Institutes of Health, Principal, 1992-1996           1,621,264

    "Training Grant on Lung Pathophysiology," National Institutes of Health T-32, Co-Investigator, 1993-2003                             3,335,310

    “The Imaging CryoMicrotome, National Institutes of Health RO1, Co-Investigator, 2001-2002 (pending)                    208,701

    “Capillary Fractal Perfusion Patterns may Protect the Lung During Microgravity, NASA, Principal, 2001-2002          22,000

       
    PUBLICATIONS
     

    Research Reports

    1. Averill, K.H., W.W. Wagner, Jr., and J.H.K. Vogel.  Studies on bronchial arterial blood flow and bronchopulmonary anastomoses. Med. Thorac. 19: 598‑608, 1962.
    2. Averill, K.H., W.W. Wagner, Jr., and J.H.K. Vogel. Correlation of right ventricular pressure with right ventricular weight. Amer. Heart J. 66: 632‑635, 1962.
    3. Vincent, T.N., R.S. Mitchell, G.F. Filley, G. Dart, L. Harris, W.W. Wagner, Jr., T. Petty, and S. Ryan.  Alveolar duct ectasia: An asymptomatic pulmonary change related to age. J. Lancet 84: 331‑336, 1964.
    4. Wagner, W.W. Jr.  Duct ectasia as studied by microradiography. Med. Thorac. 22: 188‑195, 1965.
    5. Wagner, W.W. Jr. and G.F. Filley. Microscopic observation of the lung in vivo.  Vascular Dis. 2: 229‑241, 1965.
    6. Wagner, W.W. Jr., D.B. Barker, and G.F. Filley. A photographic method for quantitating blood flow in the pulmonary microcirculation. J. Biol. Photo. Assn. 35: 95‑108, 1967.
    7. Wagner, W.W. Jr., D.B. Barker, and G.F. Filley. The bioengineering of cinemicrography of the lung in vivo. San Diego Biomed. Engineering Symp. 7: 95‑98, 1967.
    8. Wagner, W.W. Jr.  Pulmonary microcirculatory observations in vivo under physiologic condi­tions.  J. Appl. Physiol. 26: 375‑377, 1969.
    9. Wagner, W.W. Jr., L.P. Latham, P.D. Brinkman, and G.F. Filley.  Pulmonary gas transport time.  Science 163: 1210‑1211, 1969.
    10. Wagner, W.W. Jr. and D.E. Olson. Concerning pulmonary gas transport time.  Science 165: 824, 1969.
    11. Wagner, W.W. Jr, P.D. Brinkman, D.B. Barker, and G.F. Filley.  Erythrocyte photomicrography: contrast control by monochromatic transillumination.  J. Biol. Photo. Assn. 37: 156‑164, 1969.
    12. Olson, D.E., K. Horsfield, J. Wagner, W.W. Wagner, Jr., and G.F. Filley.  Investigation of flow patterns in the upper airways during mouth breathing.  Amer. Rev. Resp. Dis. 101: 456‑457, 1970
    13. Wagner, W.W. Jr. Interpretation of in vivo microscopic changes of the pulmonary micro­anatomy. Anesth. Analg. 49: 843‑845, 1970.
    14. King, E.G., W.W. Wagner, Jr., D.G. Ashbaugh, L.P. Latham, and D.R. Halsey.  Alterations in pulmonary microanatomy after fat embolism.  Chest 39: 524‑530, 1971. 
    15. Wagner, W.W. Jr., L.P. Latham, and D.R. Halsey.  The effect of hypoxia on the pulmonary microcirculation.  In Research Animals in Medicine.  L.T. Harmison (ed) DHEW(NIH) 72‑333.  Washington DC, p 253‑259, 1972.
    16. Wagner, W.W. Jr. and L.P. Latham.  Vasomotion in the pulmonary microcirculation.  In Small Vessel Angiography. S.K. Hilal (ed), Mosby, St. Louis MO, p 301‑306, 1973.
    17. Wagner, W.W. Jr., L.P. Latham, and D.R. Halsey.  The effects of hypoxia and high alveolar pres­sure on the pulmonary microcirculation.  Chest 63: 41s‑42s, 1973. 
    18. Wagner, W.W. Jr.  The effects of hypoxia on the pulmonary capillaries.  Ph.D. Disserta­tion, Colorado State University, Fort Collins CO, 1974.
    19. Wagner, W.W. Jr. and L.P. Latham.  Airway hypoxia causes pulmonary capillary recruitment in the dog.  J. Appl. Physiol. 39: 900‑905, 1975.
    20. Wagner, W.W. Jr. and L.P. Latham.  Regulation of pulmonary capillary blood flow.  In Muscu­lar exercise and the lung.  Reed CE and Dempsey J (eds), Univ Wisc Press, Madison WI, Chapter 26, p 369‑386, 1976.
    21. Hammill, S.C., W.W. Wagner W.W. Jr., L.P. Latham, W.W. Frost, and J.V. Weil. Autonomic cardiovascular control during hypoxia in the dog.  Circ. Res. 44: 569‑575, 1979.
    22. Feicht, C.B., T.S. Johnson, B.J. Martin, K.E. Sparks, and W.W. Wagner, Jr.  Secondary amenorrhea in athletes.  Lancet II (9100): 1145‑1146, 1979.
    23. Wagner, W.W. Jr., L.P. Latham, and R.L. Capen.  Capillary recruitment during airway hypoxia: the role of pulmonary artery pressure.  J. Appl. Physiol. 47: 383‑387, 1979.
    24. Reeves, J.T., W.W. Wagner, Jr., I.F. McMurtry, and R.F. Grover.  Physiological effects of high altitude on pulmonary circulation.  Int. Rev. Physiol. 20: 289‑310, 1979.
    25. Capen, R.L., L.P. Latham, and W.W. Wagner, Jr.  Diffusing capacity of the lung during hypoxia: the role of capillary recruitment.  J. Appl. Physiol. 50: 165‑171, 1981.
    26. Kuriyama, T. and W.W. Wagner, Jr.  Collateral ventilation protect against high altitude pulmonary hypertension.  J. Appl. Physiol. 51: 1251‑1256, 1981.
    27. Kuriyama, T., T. Sugita, A. Sawada, S. Watanabe, L.P. Latham, L.D. Horwitz, and W.W. Wagner, Jr.  Ex­perimental pulmonary hypertension.  Nippon Kyobu Shikkan Gakkai Zasshi 19: 820‑825, 1981.
    28. Capen, R.L. and W.W. Wagner, Jr.  Intrapulmonary blood flow redistribution during hypoxia increases gas exchange surface area.  J. Appl. Physiol. 52: 1575‑1581, 1982.
    29. Sanborn, C.F., B.J. Martin, and W.W. Wagner, Jr.  Is athletic amenorrhea specific to runners?  Am. J. Ob‑Gyn 143: 859‑861, 1982.
    30. Wagner, W.W. Jr., L.P. Latham, M.N. Gillespie, J. Guenther, and R.L. Capen.  Red cell transit times across pulmonary capillaries.  Science 218: 379‑380, 1982.
    31. Sugita, T., T.M. Hyers, I.M. Dauber, W.W. Wagner, Jr., I.F. McMurtry, and J.T. Reeves.  Lung vessel leak precedes right ventricular hypertrophy in monocrotaline treated rats.  J. Appl. Physiol. 54: 371‑374, 1983.
    32. van Grondelle, A., R.V. Ditchey, B.M. Groves, W.W. Wagner, Jr., and J.T. Reeves.  The thermodilution method overestimates low cardiac output in man.  Am. J. Physiol. 245: H690‑H692, 1983.
    33. Sugita, T., K.R. Stenmark, W.W. Wagner, Jr., P.M. Henson, J.E. Henson, T.M. Hyers, and J.T. Reeves: Abnormal alveolar cells in monocrotaline induced pulmonary hypertension.  Exptl. Lung Res. 5: 200‑215, 1983.
    34. Grover, R.F., W.W. Wagner, Jr., I.F. McMurtry, and J.T. Reeves.  The pulmonary circulation.  In The Handbook of Physiology.  Shepherd J.T. and Abboud F.M. (eds).  Waverly Press, Baltimore MD, p 103‑136, 1983. 
    35. Brooks, S.M., C.F. Sanborn, B.H. Albrecht, and W.W. Wagner, Jr.  Diet in athletic amenorrhea.  Lancet 1: 559‑560, 1984.
    36. Kuriyama, T., L.P. Latham, L.D. Horwitz, J.T. Reeves, and W.W. Wagner, Jr.  The role of collateral ventilation in maintaining ventilation‑perfusion balance.  J. Appl. Physiol. 56: 1500‑1506, 1984.
    37. Wagner, W.W. Jr. and H.B. Wagner.  A history of the pulmonary circulation.  Seminars in Respiratory Medicine 7: 117‑123, 1985.
    38. Wagner, W.W. Jr.  Control of the pulmonary circulation.  Seminars in Respiratory Medicine 7: 124‑135, 1985.
    39. Sanborn, C.F. and W.W. Wagner, Jr.  Athletic amenorrhea ‑ Chap 8, pp 125‑148.  In Female Endurance Athletes.  B.L. Drinkwater (ed).  Human Kinetics Publ. Champaign IL, 1986.
    40. Wagner, W.W. Jr., L.P. Latham, W.L. Hanson, S.E. Hofmeister, and R.L. Capen.  Vertical gradient of pulmonary capillary transit times.  J. Appl. Physiol. 61: 1270‑1274, 1986.
    41. Capen, R.L., L.P. Latham, and W.W. Wagner, Jr.  Comparison of direct and indirect measurements of pulmonary capillary transit times.  J. Appl. Physiol. 62: 1150‑1154, 1987.
    42. Lien, D.C., W.W. Wagner, Jr., R.L. Capen, C. Haslett, W.L. Hanson, S.E. Hofmeister, P.M. Henson, and G.S. Worthen.  Physiologic neutrophil sequestration in the canine pulmonary circulation: visual evidence for localization in capillaries.  J. Appl. Physiol. 62: 1236‑1243, 1987.
    43. Gadpaille, W.J., C.B. Sanborn, and W.W. Wagner, Jr.  Athletic amenorrhea, major affective disorders, and eating disorders.  Am. J. Psychiatry 144: 939‑942, 1987.
    44. Sanborn, C.F., B.H. Albrecht, and W.W. Wagner, Jr.  Athletic amenorrhea: lack of association with low body fat.  Med. Sci. Sports Exerc. 19: 207‑212, 1987.
    45. Dawson, C.A., R.L. Capen, L.P. Latham, W.L. Hanson, S.E. Hofmeister, T.A. Bronowski, D.A. Rickaby, and W.W. Wagner, Jr.  Pulmonary arterial transit times.  J. Appl. Physiol. 63: 770‑777, 1987.
    46. Sanborn, C.F. and W.W. Wagner, Jr.  Concerning hydrostatic weighing.  Med. Sci. Sports Exerc. 19: 621-622, 1987.
    47. Wagner, W.W., Jr.  The pulmonary microcirculation:  state of the art.  Chest 93: 85S - 88S, 1988.
    48. Barnard, J.W., C.E. Patterson, M.T. Hull, W.W. Wagner, Jr., and R.A. Rhoades.  Role of microvascular pressure in reactive oxygen-induced lung edema.  J. Appl. Physiol.  66: 1486-1493, 1989.
    49. Wagner, W.W. Jr. et  P.A. Hervé.  Physiologie du recrutement capillaire pulmonaire.  Rev. Mal. Resp.  6: 39-44, 1989.
    50. Wagner, W.W. Jr.  The pulmonary circulation and gas exchange, Chapter 22, pp. 645 - 664.  In Human Physiology.  R.A. Rhoades R.A. and R.P. Pflanzer (eds) Saunders, Philadelphia, 1989.
    51. Wagner, W.W. Jr. and R.A. Rhoades.   Respiration in unusual environments, Chapter 23, pp. 665 - 680.  In Human Physiology.  R.A. Rhoades and R.P. Pflanzer (eds) Saunders, Philadelphia, 1989.
    52. Hanson, W.L., J.D. Emhardt, J.P. Bartek, L.P. Latham, L.L. Checkley, R.L. Capen, and  W.W. Wagner, Jr.:  The site of recruitment in the pulmonary microcirculation.  J. Appl. Physiol.  66: 2079-2083, 1989.
    53. Herve, P., D. Musset, G. Simonneau, W.W. Wagner, Jr., and P. Duroux.  Almitrine decreases the distensibility of the large pulmonary arteries in man.  Chest 96: 572-577, 1989.
    54. Yamaguchi, T., R.F. O'Brien, W.L. Hanson, W.W. Wagner, Jr., and I.F. McMurtry. Prostacyclin synthesis contributes to inhibition of hypoxic pulmonary vasoconstriction by alkalosis.  Prostaglandins 38: 53-63, 1989.
    55. Wagner, W.W. Jr.  Direct measurement of pulmonary capillary transit time and recruitment.  In Microvascular Mechanics: Hemodynamics of Systemic and Pulmonary Microcirculation.   J.S. Lee and T.C. Skalak (eds). Springer-Verlag. New York.  163-174, 1989.
    56. Presson, R.G. Jr., K.R. Kirk, J.H. Linehan, K.A. Haselby, S. Zaleski, and W.W. Wagner, Jr.  The fate of air emboli in the pulmonary circulation.  J. Appl. Physiol. 67: 1898-1902, 1989.
    57. Berning, J.C., C.F. Sanborn, and W.W. Wagner, Jr.  Osteoporosis, diet, and exercise. In Scientific Foundations of Sports Medicine.  Teitz, C.C. (ed.) B.C. Decker.  Philadelphia. 135-152, 1989.
    58. Lien, D.C., G.S. Worthen, R.L. Capen, W.L. Hanson, L.L. Checkley, S.J. Janke, P.M. Henson, and W.W. Wagner, Jr.  Neutrophil kinetics in the pulmonary microcirculation: effects of pressure and flow in the dependent lung.  Amer. Rev. Resp. Dis.  141: 953-959, 1990.
    59. Yoder, M.C., L.L. Checkley, U. Giger, W.L. Hanson, K.R. Kirk, R.L. Capen, and W.W. Wagner, Jr.  Pulmonary microcirculatory kinetics of neutrophils deficient in leukocyte adhesion-promoting glycoproteins.  J. Appl. Physiol. 69: 207-213, 1990.
    60. Capen, R.L., W.L. Hanson, L.P. Latham, C.A. Dawson, and W.W. Wagner, Jr.  Distribution of pulmonary capillary transit times in recruited networks.  J. Appl. Physiol. 69: 473-478, 1990.
    61. Wagner, W.W. Jr.  Recruitment of pulmonary capillaries.  In Respiratory Biomechanics: Engineering Analysis of Structure and Function.  M.A.F. Epstein and J.R. Ligas (eds).  Springer-Verlag.  New York. 1990.
    62. Presson, R.G. Jr., K.R. Kirk, K.A. Haselby, and W.W. Wagner, Jr.  The effect of ventilation with soluble and diffusible gases on the size of air emboli.  J. Appl. Physiol.  70: 1068-1074, 1991.
    63. Lamm, W.E., K.R. Kirk, W.L. Hanson, W.W. Wagner, Jr., and R.K. Albert.  Flow through Zone I lungs utilizes alveolar corner vessels.  J. Appl. Physiol.  70: 1518-1523, 1991.
    64. Emhardt, J.D., S.S. Moorthy, J.W. Brown, M.D. Cohen, and W.W. Wagner, Jr.  Chest radiographic changes after cardiopulmonary bypass in children.  J. Cardiovasc. Surg.  32: 314-317, 1991.
    65. Lien, D.C., R.L. Capen, W.L. Hanson, J.E. Henson, W.W. Wagner, Jr., P.M. Henson, and G.S. Worthen.  The acute inflammatory process in the lung: direct observation of neutrophil behavior in response to C5 fragments.  Lab. Invest.  65: 145-159, 1991.
    66. Wagner, W.W. Jr.  Pulmonary capillary transit times in fully recruited networks.  In Neue Aspekte zur respiratorischen Insuffizienz.  E. Rugheimer (ed).  Springer-Verlag.  New York. 1992.
    67. Okada, O., R.G. Presson, Jr., K.R. Kirk, P.S. Godbey, R.L. Capen, and W.W. Wagner, Jr.  Capillary perfusion patterns in single alveolar walls.  J. Appl. Physiol.  72: 1838-1844, 1992.
    68. Wagner, W.W. Jr.  The pulmonary circulation and gas exchange, Chapter 22, pp. 732 - 754.  In Human Physiology, second edition.  R.A. Rhoades R.A. and R.P. Pflanzer (eds) Saunders, Philadelphia, 1992.
    69. Wagner, W.W. Jr. and R.A. Rhoades.  Respiration in unusual environments, Chapter 23, pp. 755 - 776.  In Human Physiology, second edition.  R.A. Rhoades and R.P. Pflanzer (eds) Saunders, Philadelphia, 1992.
    70. Wagner, W.W. Jr. and O. Okada.  Pulmonary capillary recruitment during airway hypoxia.  In High Altitude Medicine.  G. Ueda, J.T. Reeves, and M. Sekiguchi (eds).  Shinshu University Press. Matsumoto, Japan. 1992.
    71. Wagner, W.W., Jr.  The Bronchial Circulation. J. Butler (ed.)  Book Review.  Am. J. Physiol.  263: L729-L730, 1992.
    72. Hanger, C.C., W.W. Wagner, Jr., S.J. Janke, T.C. Lloyd, Jr., and R.L. Capen.  Computer simulation of neutrophil movement through the pulmonary capillary bed.  J. Appl. Physiol.  74: 1647-1652, 1993.
    73. Hanson, W.L., D.F. Boggs, J.M. Kay, S.E. Hofmeister, and W.W. Wagner, Jr.  Collateral ventilation and pulmonary arterial smooth muscle in the coati mundi.  J. Appl. Physiol.  74: 2219-2224, 1993.
    74. Means, L.J., W.L. Hanson, K.O. Mounts, and W.W. Wagner, Jr.  Pulmonary capillary recruitment in neonatal lambs.  Pediatr. Res. 34: 596-599, 1993.
    75. Wagner, W.W., Jr.  Pulmonary capillary perfusion by plasma. (invited editorial). J. Appl. Physiol.  75: 1437-1438, 1993.
    76. Wagner, W.W., Jr. and R.G. Presson, Jr.  Gas exchange reserve during hypoxia: role of capillary recruitment. pp 77-88.  In Hipoxia: Investigaciones Basicas Y Clinicas.   F. León-Velarde and A. Arregui (eds). UPCH/IFEA, Lima, 1993.
    77. Hillier, S.C., P.S. Godbey, C.C. Hanger, J.A. Graham, R.G. Presson, Jr., O. Okada, J.H. Linehan, C.A. Dawson, and W.W. Wagner, Jr.  Direct measurement of pulmonary microvascular distensibility.  J. Appl. Physiol. 75: 2106-2111, 1993.
    78. Wagner, W.W., Jr. and E.K. Weir. (eds.) The Pulmonary Circulation and Gas Exchange.  Futura, Mount Kisco, NY. 1994.
    79. Okada, O., R.G. Presson, Jr., P.S. Godbey, R.L. Capen, and W.W. Wagner, Jr.  Temporal capillary perfusion patterns in single alveolar walls of intact dogs.  J. Appl. Physiol.  76: 380-386, 1994.
    80. Presson, R.G., Jr., C.C. Hanger, P.S. Godbey, J.A. Graham, T.C. Lloyd, Jr., and W.W. Wagner, Jr.  The effect of increasing flow on the distribution of pulmonary capillary transit times.  J. Appl. Physiol.  76: 1701-1711, 1994.
    81. Presson, R.G., Jr., O. Okada, P.S. Godbey, J.A. Graham, C.C. Hanger, R.W. Glenny, and W.W. Wagner, Jr.  Stability of alveolar capillary opening pressures.  J. Appl. Physiol. 77: 1630-1637, 1994.
    82. Presson, R.G., Jr., J.A. Graham, C.C. Hanger, P.S. Godbey, S.A. Gebb, R.A. Sidner, R.W. Glenny, and W.W. Wagner, Jr.  Distribution of pulmonary capillary erythrocyte transit times.  J. Appl. Physiol. 79: 382-388, 1995.
    83. Gebb, S.A., J.A. Graham, C.C. Hanger, P.S. Godbey, R.L. Capen, C.M. Doerschuk, and W.W. Wagner, Jr.  Sites of leukocyte sequestration in the pulmonary microcirculation.  J. Appl. Physiol. 79: 493-497, 1995.
    84. Hanger, C.C., S.C. Hillier, R.G. Presson, Jr., R.W. Glenny, and W.W. Wagner, Jr.  Measuring pulmonary microvessel diameters using video image analysis.  J. Appl. Physiol. 79: 526-532, 1995.
    85. Godbey, P.S., J.A. Graham, R.G. Presson, Jr., W.W. Wagner, Jr., and T.C. Lloyd, Jr.  The effect of capillary pressure and lung distention on capillary recruitment.  J. Appl. Physiol. 79: 1142-1147, 1995.
    86. Wagner, W.W. Jr. and R.A. Rhoades.  The pulmonary circulation, gas exchange, Chapter 21, pp. 639 - 634.  In Human Physiology, third edition.  R.A. Rhoades R.A. and R.P. Pflanzer (eds) Saunders, Philadelphia, 1995.
    87. Wagner, W.W. Jr. and R.A. Rhoades.  Environmental physiology.  Chapter 29, pp. 853 - 884.  In Human Physiology, third edition.  R.A. Rhoades and R.P. Pflanzer (eds) Saunders, Philadelphia, 1995.
    88. Short, A.C., M.L. Montoya, S.A. Gebb, R.G. Presson, Jr., W.W. Wagner, Jr., and R.L. Capen.  Pulmonary capillary diameters and recruitment characteristics in subpleural and interior networks.  J. Appl. Physiol. 80: 1568-1573, 1996.
    89. Wagner, W.W. Jr. Recruitment of gas exchange vessels. In The Lung: Scientific Foundations, 2nd Edition.  Crystal, R.G., J.B. West, E.R. Weibel, and P.J. Barnes (eds.) pp 1537-1547. Raven, New York, 1996.
    90. Hanger, C.C., R.G. Presson, Jr., O. Okada, S.J. Janke, J.J. Watkins, W.W. Wagner, Jr., and R.L. Capen.  Computer determination of perfusion patterns in pulmonary capillary networks.  J. Appl. Physiol.  82: 1283-1289, 1997.
    91. Hillier, S.C., J.A. Graham, C.C. Hanger, P.S. Godbey, R.W. Glenny, and W.W. Wagner, Jr.  Hypoxic vasoconstriction in pulmonary arterioles and venules.  J. Appl. Physiol. 82:1084-1090, 1997.
    92. Presson, R.G., Jr., T.M. Todoran, B.J. DeWitt, I.F. McMurtry, and W.W. Wagner, Jr.  Capillary recruitment and transit time in the rat lung.  J. Appl. Physiol.  83: 543-549, 1997.
    93. Presson, R.G., Jr., C.C. Hanger, J.A. Graham, G.M. Zenk, R.A. Sidner, P.S. Godbey, T.M. Todoran, and W.W. Wagner, Jr.  Pulmonary microvascular flow changes after vessel occlusion.  J. Appl. Physiol. 84: 303-310, 1998.
    94. Wagner, W.W. Jr., and R.G. Presson, Jr.  Complexity of perfusion in the pulmonary gas exchange vessels.  In Complexity in Structure and Function of the Lung.  Hlastala M.P., and H.T. Robertson (eds.) pp 429 - 460 Marcel Dekker, New York. 1998.
    95. Tanabe, N., T.M. Todoran, G.M. Zenk, B.R. Bunton, W.W. Wagner, Jr., and R.G. Presson, Jr.  Perfusion heterogeneity in the pulmonary acinus.  J. Appl. Physiol.  84: 933-938, 1998.
    96. Wagner, W.W., Jr., T.M. Todoran, N. Tanabe, T.M. Wagner, J.A. Tanner, R.W. Glenny, and R.G. Presson. Jr.  Pulmonary capillary perfusion: intra-alveolar fractal patterns and interalveolar independence.  J. Appl. Physiol. 86: 825 - 831, 1999.
    97. Hanson, W.L., D.F. Boggs, J.M. Kay, S.E. Hofmeister, O. Okada, and W.W. Wagner, Jr.  Pulmonary vascular response of the coati to chronic hypoxia.  J. Appl. Physiol. 88: 981-986, 2000.
    98. Tanabe, N., T.M. Todoran, G.M. Zenk, J. Aono, W.W. Wagner, Jr., and R.G. Presson, Jr.  Mechanism of pulmonary acinar perfusion heterogeneity.  J. Appl. Physiol. 89: 1943-1948, 2000.
    99. Glenny, R.W., W.J. Lamm, S.L. Bernard, D. An, M. Chornuk, S.L. Pool, W.W. Wagner, Jr., M.P. Hlastala, and H.T. Robertson.  Selected Contribution: Redistribution of pulmonary perfusion during weightlessness and increased gravity.  J. Appl. Physiol. 89: 1239-1248, 2000.
    100. Jaryszak, E.M., W.A. Baumgartner, A.J. Peterson, R.G. Presson, Jr., R.W. Glenny, and W.W. Wagner, Jr.  Selected Contribution:  Response of the pulmonary capillaries to sudden changes in flow.  J. Appl. Physiol. 89: 1233-1238, 2000.
    101. Jaryszak, E.M.,  W.A. Baumgartner, A.J. Peterson, R.G. Presson, Jr., R.W. Glenny, and W.W. Wagner, Jr.Video clip:  Response of the pulmonary capillaries to sudden changes in flow, 2000. http://jap/physiology.org/cgi/content/full/89/3/1233/DC1
    102. Presson, R.G., Jr., W.A. Baumgartner, Jr., A.J. Peterson, R.W. Glenny, and W.W. Wagner, Jr.  Pulmonary capillary recruitment lowers vascular resistance during pulsatile flow.  J. Appl. Physiol. 92: 1183-1190, 2002.
    103. Presson, R.G., Jr., W.A. Baumgartner, Jr., A.J. Peterson, R.W. Glenny, and W.W. Wagner, Jr.  Pulmonary capillary recruitment lowers vascular resistance during pulsatile flow.  J. Appl. Physiol. http://jap/physiology.org/cgi/content/full/92/3/1183/DC1
    104. Wagner, W.W. Jr.  Leukocyte and erythrocyte kinetics in the pulmonary microcirculation.  In Blood Elements and the Pulmonary Circulation.  E.K. Weir, H.L. Reeve, and J.T. Reeves (eds.) pp 317 - 338 Futura, Armonk, NY 2002.
    105. Wagner, W.W. Jr. and R.A. Rhoades.  The pulmonary circulation and gas exchange In Human Physiology, fourth edition.  R.A. Rhoades and R.P. Pflanzer (eds) Saunders, Philadelphia, 2003.
    106. Wagner, W.W., Jr.  Attitudes on Altitudes.   J.T. Reeves and R.F. Grover (eds.) Book Review.  The Physiologist.  45: 122, 2002.
    107. Nabors, L.K., W.A. Baumgartner, Jr., S.J. Janke, J.R. Rose, W.W. Wagner, Jr., and R.L. Capen.  Red blood cell   orientation in pulmonary capillaries.  J. Appl. Physiol.  94: 1634-1640, 2003.
    108. Baumgartner, W.A. Jr., E.M. Jaryszak, A.J. Peterson, R.G. Presson, Jr., and W.W. Wagner, Jr.  Heterogeneous capillary recruitment among adjoining alveoli.  J. Appl. Physiol.  95: 469-476, 2003.
    109. Rodefeld, M.D., J.A. Boyd, C.D. Myers, R.G. Presson, Jr., W.W. Wagner, Jr., J.W. Brown.  Cavopulmonary assist in the newborn: an alternative strategy for single ventricle palliation.  J. Thorac.  Cardiovasc. Surg. 127: 705-711, 2004. 
    110. Baumgartner, W.A. Jr., A.J. Peterson, R.G. Presson, Jr., N. Tanabe, E.M. Jaryszak, and W.W. Wagner, Jr.  Increased hematocrit reduces blood flow switching among pulmonary capillaries.  J. Appl. Physiol. 97:522-526, 2004.
    111. Lamm, W.J.E., S.L. Bernard, W.W. Wagner, Jr., and R.W. Glenny.  Intravital Microscopic Observation of 15 μm microspheres lodging in the pulmonary microcirculation.  J. Appl. Physiol.98:2242-2248, 2005.
    112. Wagner, W.W., Jr., and R.G. Presson, Jr. Forms of reserve in the pulmonary capillaries.  Encyclopedia of the Microvasculature. 497-503,2006, D. Shepro ed.  Elsevier, San Diego. Elsevier Academic Press, Amsterdam.
    113. Wagner, W.W., Jr., W.J. Lamm, S.L. Bernard, D, An, M. Chornuk, S.L. Pool, M.P. Hlastala, H.T. Robertson, and R.W. Glenny.  Paradoxical redistribution of pulmonary blood flow in the lateral posture: comparing microgravity and increased gravity.  J. Grav. Physiol,. (in press).
    114. Lamm, W.J.E., S.L. Bernard, W.W. Wagner, Jr., and R.W. Glenny.  Intravital Microscopic Observation of 15 μm microspheres lodging in the pulmonary microcirculation.  J. Appl. Physiol.98:2242-2248, 2005.
    115. Jaryszak, E.M., A.J. Peterson, D.T. Sines, R.G. Presson, Jr., and W.W. Wagner, Jr.  Unexpected temporal redistribution of pulmonary capillary blood flow.  J. Appl. Physiol. (submitted).
    116. Wiltz W. Wagner, Jr, W.J. Lamm, S.L.Bernard, A. Dowon M. Chornuk, S.L. Pool, Dowon An, M.Chornuk,, M.P. Hlastala,H.T.,and  R. W. Glenny. Paradoxical redistribution of pulmonary blood flow in the left lateral Posture.Comparing Microgravity and Increased Gravity. J. Grav. Physiol. (in press)
       
       
      Update: Apr. 19,2007