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Chun Zhou, M.D., Ph.D.

Chun Zhou, M.D., Ph.D.
Phone: (251) 460-7485
Fax: (251) 460-6798
Email: czhou@jaguar1.usouthal.edu

EDUCATION

02/2005 – Now

Post-doctoral Fellow
Department of Pharmacology, Center of Lung biology, University of South Alabama

03/2001 – 12/2004

Ph. D
Department of Pharmacology and Toxicology, Otto-von-Guericke University Magdeburg

09/1996 – 07/1999

M.S.
Department of Physiology, Dalian Medical University, Dalian, China

09/1987 – 07/1993

M.D.
Norman Bethune’s University of Medical Sciences, Changchun, China

EXPERIENCE

02/2005 – Now

Post-doctoral Fellow
Department of Pharmacology, Center of Lung biology, University of South Alabama

03/2001 – 12/2004

Ph. D
Department of Pharmacology and Toxicology, Otto-von-Guericke University Magdeburg

10/1999 – 10/2000

Visiting Scientist
Institute of Pharmacology and Toxicology, University Innsbruck, Austria

07/1998 – 02/2001

Lecturer
Department of Physiology, Dalian Medical University, Dalian, China

07/1993 – 06/1998

Teaching Assistant
Department of Physiology, Dalian Medical University, Dalian, China

MEMBERSHIP

  • American Physiological Society, since 2005

PUBLICATIONS
  1. Wu S, Jian MY, Xu YC, Zhou C, Al-Mehdi AB, Liedtke W, Shin HS, Townsley MI. Ca2+ entry via α1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium. Am J Physiol Lung Cell Mol Physiol. 2009;297(4):L650–L657.
  2. Lu F, Chen H, Zhou C, Liu S, Guo M, Chen P, Zhuang H, Xie D, Wu S. T-type Ca2+ channel expression in human esophageal carcinomas: a functional role in proliferation. Cell Calcium. 2008;43(1):49-58.
  3. Zhou C, Chen H, Lu F, Sellak H, Daigle JA, Alexeyev MF, Xi Y, Ju J, van Mourik JA, Wu S. CaV3.1 (α1G) controls von Willebrand factor secretion in rat pulmonary microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2007;292(4):L833-844.
  4. Zhou C, Wu S. T-type calcium channels in pulmonary vascular endothelium. Microcirculation. 2006;13(8):645-656.
  5. Lu F, Chen H, Zhou C, Wu S. Is there a role for T-type Ca2+ channel in glioma cell proliferation? Cell Calcium. 2005;38(6):593-595.
  6. Stumm R, Rüthrich H, Schulz S, Zhou C, and Hollt V. Expression of the m-opioid receptor is induced in dentate gyrus granule cells after focal cerebrocortical ischaemia and stimulation of entorhinal afferents. Eur J Neurosci. 2005;22(5):1032-44.
  7. Stumm RK*, Zhou C*, Schulz S, Endres M, Kronenberg G, Allen JP, Tulipano G, and Höllt V. *equal author. Somatostatin receptor 2 is activated in cortical neurons and contributes to neurodegeneration after focal ischemia. J Neurosci. 2004;24(50):11404-11415.
  8. Stumm RK, Zhou C, Schulz S, and Höllt V. Neuronal types expressing mu- and delta-opioid receptor mRNA in the rat hippocampal formation. J Comp Neurol. 2004;469(1):107-118.
  9. Stumm RK, Zhou C, Ara T, Lazarini F, Dubois-Dalcq M, Nagasawa T, Höllt V, and Schulz S. CXCR4 regulates interneuron migration in the developing neocortex. J Neurosci. 2003;23(12):5123-5130.
  10. Zhou C, Chen ZW, and Zhang WQ. Mini-osmeotic pump, a new method for delivering drug continuously and regularly in awaking experimental animals. Chinese Journal of Microecology, 1997;9(3):53.

PRESENTATIONS

Oral: A Potential Role of SST2 in Focal Cerebral Ischemia. 22nd Blankenese Conference, 2002, Hamburg, Germany

ABSTRACTS
  1. Townsley MI, Jian MY, Xu YC, Zhou C, Al-Mehdi, AB, Liedtke W, Shin HS, and Wu S.  Ca2+ entry via α1G and TRPV4 channels differentially regulates alveolar capillary endothelium. FASEB J. 2009 23:999.9
  2. Zhou C, Chen H, King JA, Sellak H, Kuebler WM, Yin J, Shin HS, Townsley MI, and Wu S.  A distinct subcellular pool and an α1G T-type Ca2+ channel regulated surface expression of P-selectin in pulmonary capillary endothelium. FASEB J. 2009 23:964.13
  3. Sellak H, Liu B, Zhou C, Chen H, and Wu S. Mechanism of hypoxia-induced α1H (CaV3.2) gene expression: examining the transcriptional regulation. FASEB J, 2008; 22:960.20.
  4. Zhou C, Liu B, Sellak H, Shin HS, and Wu S. α1G T-type Ca2+ channel controls plasma membrane P-selectin expression in pulmonary microvascular endothelial cells. FASEB J, 2007. 21(6): A1433 #977.17.
  5. Chen H, Lu F, Zhou C, Guo M, and Wu S. T-type Ca2+ channel expression in human esophageal carcinomas: a functional role in proliferation. FASEB J, 2007. 21(6): A538 #604.13.
  6. Kuebler WM, Chen H, Yin J, Zhou C, and Wu S. Depolarization evokes calcium entry trough CaV3.1 channels in lung microvascular endothelium in situ. FASEB J, 2006. 20(4): A749 #469.26.
  7. Chen H, Zhou C, Creighton J, Sellak H, and Wu S. Regulation of CaV3.1 T-type Ca2+ channel expression by cAMP in pulmonary microvascular endothelial cells. FASEB J, 2006. 20(4): A749 #469.25.
  8. Zhou C, Chen H, Daigle JA, van Mourik JA, and Wu S. CaV3.1 (α1G) controls von Willebrand factor secretion in pulmonary microvascular endothelial cells. FASEB J, 2006. 20(4): A748 #469.19.
  9. Zhou C, Stumm RK, Schäfer K, Rauca C, Schulz S, and Höllt V. A role of somatostatin in focal cerebral ischemia neuroprotection and neuro-repair. 3rd International Symposium, 2003, Magdeburg, Germany
  10. Stumm RK, Zhou C, Lauarini F, Dubois-Dalcq M, Ara T, Nagasawa T, Junker V, Culmsee C, Kriglstein J, Höllt V, and Schulz S. The SDF-1 chemkine receptor CXCR4 directs cellar migration in the embryonic and leisioned adult brain neuroprotection and neurorepair. 3rd International Symposium, 2003, Magdeburg, Germany.
  11. Zhou C, Stumm RK, Schulz S, and Höllt V. A potential role of sst2 in focal cerebral ischemia. 22nd Blankenese Conference, 2002, Hamburg, Germany
  12. Zhou C, Stumm RK, Rüthrich H, Wagner M, and Höllt V. Long-term potentiation alters gene-expression of opiods but not of µ-opioid-receptors in the dentate gyrus. 43rd Spring Meeting Deutsch Gesellschaft für experimentelle und klinische Pharmakologie und Toxiologie, 2002, Mainz, Germany
  13. Stumm RK, Zhou C, Schulz S, Rüthrich H, Schäfer M, Wagner M, and Höllt V. Temporal dynamics of cellular opioid and opioid receptor gene-expression during hippocampal long-term potentiation (LTP). INRC Meeting, 2001, Helsinki, Finland

LANGUAGES

Chinese, English, German
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