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EDUCATION |
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1989 B.Sc. (Honors) |
University of Northumberland, England |
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Environmental Science |
1999 |
Pensacola Junior College, Pensacola, FL |
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Undergraduate classes in basic sciences |
In progress Ph.D |
University of South Alabama, Mobile, AL |
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HONORS AND AWARDS |
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Pensacola Junior College: |
President’s list 1998-99 |
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Leadership award in Biological Sciences
Physical Sciences Department Scholar |
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PROFESSIONAL SOCIETIES |
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American Physiological Society
Member Phi Theta Kappa Academic Honorary Society
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UNIVERSITY SERVICE |
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University of Northumberland: |
Student Representative as member |
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of Faculty Review Board 1986-89 |
Pensacola Junior College: |
President of the Biology Club 1998-99 |
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1998-99 Student tutor in biological sciences |
University of South Alabama: |
Basic Medical Science Student |
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Organization |
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1999-2000 First Year Representative
2001-2002 President
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RESEARCH FUNDING |
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2003-2005 American Heart association Predoctoral Fellowship Award
Pseudomonas aeruginosa adenylyl cyclase synthesizes cAMP that induces pulmonary microvascular gap formation
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PUBLICATIONS |
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1. Kang H, Sayner SL, Gross KL, Russell LC, Chinkers M. Identification of amino acids in the tetratricopeptide repeat and c-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation. Biochemistry 2001 Sep 4;40(35):10485-90
2. Sarah L. Sayner, Dara Frank, Judy King, John VandeWaa, and Troy Stevens Pseudomonas aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP Causing Intercellular Gap Formation in Pulmonary Microvascular Endothelium (in preparation)
3. Sarah Sayner, and Troy Stevens “Regulation of Endothelial cAMP” In Lung Endothelial in Health and Disease, edited by Carolyn E. Patterson (in preparation)
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ABSTRACTS |
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1. Sayner, S.L., Frank, D., VandeWaa, J., Stevens, T., Functional Association of Endogenous Adenylyl Cyclases and Phosphodiesterases in Pulmonary Microvascular Endothelial Cells Revealed by the Expression of Exogenous P. aeruginosa Adenylyl Cyclase, ExoY. FASEB J., 2003
2. Sayner, S.L., Frank, D., VandeWaa, J., Stevens, T., P. aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP Causing Intercellular Gap Formation in Pulmonary Microvascular Endothelium. FASEB J., 2003
3. King, J., Wu, S., Cioffi, D.L., Sayner, S.L., Stevens, T., Inhibition of Type 4 Phosphodiesterase Induces Abluminal Translocation of Endoplasmic Reticulum Tubules in Lung Microvascular Endothelial Cells. FASEB 2003
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PRESENTATIONS |
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1. Center for Lung Biology and Division of Pulmonary and Critical Care Medicine, University of South Alabama, Mobile, AL 2003. “P. aeruginosa exotoxins and virulence: role of adenylyl cyclase, exoY, in lung endothelial permeability.”
2. Experimental Biology, International Convention, San Diego, CA 2003. “P. aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP causing Intercellular Gap Formation in Pulmonary Microvascular Endothelial Cells”.
3. Experimental Biology, International Convention, San Diego, CA 2003. Graduate Student Highlights in Respiratory Physiology “P. aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP causing Intercellular Gap Formation in Pulmonary Microvascular Endothelial Cells”.
4. University of Cambridge, Department of Pharmacology, UK 2003. “ExoY Adenylyl Cyclase of P. aeruginosa generates a phosphodiesterase insensitive cAMP pool and induces pulmonary endothelial gap formation.”
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