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EDUCATIONAL HISTORY |
Institution/Location |
Degree |
Year Conferred |
Field |
Newberry College |
B.S. |
2000 |
Biology |
Newberry, SC |
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University of South Alabama |
Ph.D. |
In Progress |
Lung Biology |
Mobile, AL |
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| RESEARCH AND PROFESSIONAL EXPERIENCE |
| 2002-present |
Graduate Research Assistant
Department of Pharmacology/Center of Lung Biology
University of South Alabama
Mobile, AL 36688 |
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| RESEARCH ACTIVITES AND INTERESTS |
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My current research focuses on the role of Angiopoietin-1 in tumor growth and vasculogenesis. Angiopoietin-1 is a secreted protein known to prevent the formation of ‘leaky’ blood vessels as well as to act as a chemoattractant for smooth muscle cells and pericytes. Recent research has been filled with controversy over the actions of Angiopoietin-1 in tumors. Some studies show Angiopoietin-1 promotes tumor growth while others demonstrate an inhibitory effect on tumor growth. Currently immunoblots are being used to determine the presence of Angiopoietin-1 and its receptor Tie-2 in various mouse and human cancer cell lines. In the works are an immunohistochemical analysis and future plans for determining the effect of Angiopoietin-1 on experimental metastasis and tumor growth through transfection of Ang-1 cDNA and shRNA into the various cell lines. |
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| 1. Al-Mehdi AB, Patel MR, Haroon A, Reed DJ, Ohlsson-Wilhelm R, Muirhead K, and Gray BD. Increased depth of cellular imaging in the intact lung using far red and near infrared fluorescent probes. IJBI. Volume 2006. Article ID 37470 (7 pages) |
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1. Reed DJ, Al-Mehdi AB. Metastatic intravasation by hypoxic vasoattraction. Gulf Coast Physiological Society (2004).
2. Reed DJ, Fodstad O, Al-Mehdi AB. PO2 and adenosine dependent cancer cell migration during intravasation. AACR (2005).
3. Reed DJ, Al-Mehdi AB. Role of Angiopoietin-1 in Tumor Blood Vessel Formation. MD Anderson Conference (2006).
4. Reed DJ, El-Zarrad MK, Al-Mehdi AB. Angiopoietin-1 in Lung Tumor Blood Vessel Formation. AACR (2007).
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| PRESENTATIONS |
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“Research in Progress”, Center of Lung Biology, University of South Alabama; October 2004, November 2005, and March 04, 05 & 07. |
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| UNIVERSITY EXPERIENCE |
| 2002-present |
Participant, Relay for Life, University of South Alabama |
| 2005-present |
Student Representative, Biomedical Library Advisory Committee,
University of South Alabama |
| 2006-2007 |
Instructor, BEAR Program |
2005-2006 |
Student Representative, BMS Graduate Program Executive
Committee, University of South Alabama |
| 2005-2006 |
President, Basic Medical Science Student Organization,
University of South Alabama |
2005 |
Workshop Presenter, Expanding Your Horizons Conference,
University of South Alabama |
| 2004-2005 |
Vice President, Basic Medical Science Student Organization,
University of South Alabama |
| 2002-2004 |
Assistant, Expanding Your Horizons Conference,
University of South Alabama |
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| Last Update: June 26, 2007 |
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