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International Birth Defects Information System



Pregnancy " Triple Test "

Pregnant women are routinely offered a blood test called a triple test. This screening test (not diagnostic) measures the amount of three specific proteins in a pregnant woman's blood. This test is also known as: Triple Screen, AFP Plus, Multiple Marker Test, or Prenatal Risk Profile Test.

This "triple test" is mainly used to identify pregnancies which may be at increased risk for:

  • Down syndrome
  • Neural tube defects NTD (spina bifida or anencephaly)
  • Other birth defects
Abnormal results must be confirmed by a diagnostic test (amniocentesis) combined with a high resolution ultrasound performed by an expert in birth defects and laboratory studies of the amniotic fluid and cells including chromosome studies.


University of South Alabama
Birth Defects Genetics Center - Mobile, Alabama 36688-0002 / 251-460-7500
For questions or comments contact us or call toll free 1-800-624-1865
Date last changed: April 16, 2003 2:41 PM
http://www.southalabama.edu/genetics