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USA Health System
News Release
Mobile, Ala. (September 10, 2009)
Contact: Ashley Gruner, (251) 460-1682

Study Shows Smaller Dose Equally Effective in Colonoscopy Preparation

The work of Dr. Jack A. Di Palma, a gastroenterologist and professor of internal medicine at the University of South Alabama, was recently published in the current issue of the American Journal of Gastroenterology. The study evaluates a new, colon-cleansing solution to prepare adults for a colonoscopy.

For a colonoscopy to be performed properly, the colon must be free of solid matter. Current colon-cleansing solutions are isotonic, meaning patients must ingest upwards of a gallon of fluid for effective purging. Patients often complain of the amount of solution that must be ingested.


Dr. Di Palma said the low-volume, oral sulfate solution in the study provides a more tolerable way of preparing the bowel for colonoscopy. “The study confirmed that this new solution produces the same degree of cleansing as other solutions,” he said. “In addition, preparation-related symptoms of cramping, bloating, nausea, and vomiting were generally mild and infrequent.”


A colonoscopy is an exam used to detect changes or abnormalities in the large intestine (colon) and rectum. It is often used as a standard procedure for detecting colon cancer.


During a colonoscopy, a long, flexible tube is inserted into the rectum. A tiny video camera at the tip of the tube allows the doctor to view the inside of the entire colon. If necessary, abnormal tissue can be removed through the scope during a colonoscopy.

Dr. Di Palma is medical director of the USA Digestive Health Center and director of the division of gastroenterology at USA. His special interests include Crohn’s disease, ulcerative colitis, acid reflux, lactose intolerance, irritable bowel syndrome and stomach ulcers. The USA Digestive Health Center is located at Infirmary West Pavilion.


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Date last changed: September 10, 2009 4:34 PM