USA Mitchell Cancer Institute - Michael R. Boyd, M.D., Ph.D.

Michael R. Boyd, M.D., Ph.D.

Abraham Mitchell Chair and Director and Professor of Medicine
and Pharmacology, USA College of Medicine

Contact Information:

USA-Mitchell Cancer Institute
1660 Springhill Avenue, Mobile, AL 36607
Telephone: (251) 460-7307
Fax: (251) 460-6994
Email: mboyd@usouthal.edu

Background:

Ph.D., Pharmacology and Organic Chemistry, Vanderbilt University, 1975
M.D., Vanderbilt University, 1975

National Cancer Institute, Bethesda, MD

Staff Fellow, 1975-76 Head, Molecular Toxicology Section, 1976-80

Chief, Laboratory of Experimental Therapeutics and Metabolism, 1980-84

Director, Developmental Therapeutics Program, 1984-1990

Chief, Laboratory of Drug Discovery Research and Development, 1990-2001

Director, Molecular Targets Development Program, 2001-02

University of South Alabama, Mobile, Alabama, April 2002-Present

Research Interests:

Anticancer and antiviral drug discovery and development

Selected Recent Publications :

Boyd, M.R. : The NCI human tumor cell line (A60-cell@) screen; concept, implementation and applications. In: Teicher, B.A., and Andrews, P.A. (eds.): Anticancer Drug Development Guide; Preclinical Screening, Clinical Trials, and Approval; Humana Press, 2004, pp 41-62.

Tsai, C-C., Emau, P., Jiang, Y., Agy, M.B., Song, X., Schmidt, A., Morton, W.R., Shattock, R., Gustafson, K.R., Boyd, M.R. : Cyanovirin-N blocks HIV infection of human cervical explants and vaginal transmission of SHIV infection in macaques. AIDS Res. Hum. Retrovir. 20: 11-18, 2004.

Bowman, E.J., Gustafson, K.R., Bowman, B.J., Boyd, M.R .: Identification of a new chondropsin-class of antitumor compound that selectively inhibits V-ATPases. J. Biol. Chem. 278: 44147-44152, 2003.

Bokesch, H.R., O. Keefe, B.R., Pannell, L.K., Patterson, G.M.L., McKee, T.C., Gardella, R.S., Sowder, R.C. II, Burrier, J., Watson, K., Buckheitt, R.W., Boyd, M.R .: A novel anti-HIV protein from Scytonema varium. Biochemistry, 42: 2578-2584, 2003.

Shenoy, S.R., Barrientos, L.G., Ratner, D.M., O. Keefe, B.R., Seeberger, P.H., Gronenborn, A.M., Boyd, M.R .: NMR and calorimetric titration studies of the anti-HIV protein cyanovirin-N with branched oligomannosides: characterization of multivalent and multi-site binding. Chem. Biol., 9: 1109-1118, 2002.

Rashid, M.A., Gustafson, K.R., Crouch, R.C., Groweiss, A., Pannell, L.K., Van, Q.N., Boyd, M.R .: Application of high-field NMR and cryoprobe technologies in the structural elucidation of poecillastrin A, a new cytotoxic macrolide lactam from the sponge, Poecillastra sp. Organic Lett. 19: 3293-3296, 2002.