A fine balance exists between productive immune responses generating protection from pathogens, and counter-productive responses that lead to autoimmune disease. My lab focuses on understanding the cellular and molecular pathways responsible for directing B cell fate decisions that ultimately result in antibody production. We utilize genetic mouse strains to explore more efficient vaccine design and to model human autoimmune disease.
Recent Publications
Zhang H, Li J, Barrington RA, Liang G, Qin G, Liu DX. 2007. An anti-endotoxin peptide that generates from the amino-terminal domain of complement regulatory protein C1 inhibitor. Biochem Biophys Res Commun 359(2):285-91.
Zhang H, Qin G, Liang G, Li J, Chiu I, Barrington RA, Liu D. 2007. Suppression of complement regulatory protein C1 inhibitor in vascular endothelial activation by inhibiting vascular cell adhesion molecule-1. Biochem Biophys Res Commun 358(4):1120-7.
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