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A
Multicenter Double-Blinded Study In Patients With Compensated
Cirrhosis Due To Chronic Hepatitis C Who Are Non-Responders
To Prior Interferon Alfa Or interferon Alfa + Ribavirin Therapy,
Comparing Treatment With Thymosin Alpha 1 + PEG-Interferon
Alfa-2A With PEG-interferon Alfa-2a + Placebo.
Lead investigator: Jorge L. Herrera
M.D.
Investigational agents: Pegylated interferon alfa-2a (Pegasys)
and thymosin alpha 1 (Zadaxin).
Study Subjects: Patients with chronic hepatitis C infection
who have biopsy proven stage 3 or 4 fibrosis, compensated
liver disease, and have received at least 24 weeks of non-pegylated
antiviral therapy and failed to clear virus.
A
Randomized, Open-label, Multicenter, Efficacy and Safety Study
Examining the Effects of Duration of Treatment and of a High
Induction Dose of Pegasys in combination with daily Copegus
in Patients with Chronic Hepatitis C who did not respond to
previous Peginterferon with alfa-2b/ribavirin Combination.
Lead
Investigator: Jorge L. Herrera, M.D.
Investigational
Agents: Peginterferon alfa-2a and ribavirin
Study
Subjects: Patients who failed therapy with Peginterferon alfa-2b(Peg-intron)
and ribavirin |