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Hyalgan is a synthetic joint fluid made from rooster combs which is indicated mild to moderate arthritis. It is administered as a knee injection given once a week for 3-5 weeks. Hyalgan has been shown to provide improved shock absorption, cartilage nutrition, and pain in patients with osteoarthritis. Hyalgan candidates have mild to moderate arthritis with significant knee pain and wish to avoid surgery. The ongoing study involves evaluating patients with either 3 or 5 injections of Hyalgan. Enrolled patients are randomly assigned to 2 groups: 1) 5 weekly injections of Hyalgan or 2) 3 weekly injections of Hyalgan + 2 weekly injections of saline. Both the patient and physician are blinded to which group the patient is assigned. The USA Sports Medicine & Joint Reconstruction doctors hope to determine which injection regimen is superior in the treatment of knee osteoarthritis. If you are interested in this study, please e-mail online or contact the Sports Medicine/Joint Restoration Service staff and we will contact you.
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