Welcome to the Borchert Lab

Research in the Borchert laboratory explores the regulation of gene expression by small RNAs. Our main focuses are on microRNAs (miRNAs), which are ~20 nucleotide RNAs that repress gene expression by base-pairing to messenger RNAs transcribed from specific protein-coding genes, and sRNAs, similarly functioning short noncoding RNAs in prokaryotes. Our lab examines the roles these noncoding RNAs play during growth and development, how they contribute to speciation, and how their misregulations contribute to disease and oncogenesis.